Slow binocular rivalry in bipolar disorder

Miller, S.M., Gynther, B.D., Heslop, K.R., Liu, G.B., Mitchell, P.B., Ngo, T.T., Pettigrew, J.D. and Geffen, L.B. (2003) Slow binocular rivalry in bipolar disorder. Psychological Medicine, 33 4: 683-692. doi:10.1017/S0033291703007475

Author Miller, S.M.
Gynther, B.D.
Heslop, K.R.
Liu, G.B.
Mitchell, P.B.
Ngo, T.T.
Pettigrew, J.D.
Geffen, L.B.
Title Slow binocular rivalry in bipolar disorder
Journal name Psychological Medicine   Check publisher's open access policy
ISSN 1469-8978
Publication date 2003-05
Sub-type Article (original research)
DOI 10.1017/S0033291703007475
Volume 33
Issue 4
Start page 683
End page 692
Total pages 10
Editor Eugene Paykel
Kenneth S. Kendler
Place of publication Cambridge, England
Publisher Cambridge University Press
Collection year 2003
Language eng
Subject C1
380101 Sensory Processes, Perception and Performance
730211 Mental health
Abstract Background. The rate of binocular rivalry has been reported to be slower in subjects with bipolar disorder than in controls when tested with drifting, vertical and horizontal gratings of high spatial frequency. Method. Here we assess the rate of binocular rivalry with stationary, vertical and horizontal gratings of low spatial frequency in 30 subjects with bipolar disorder, 30 age- and sex-matched controls, 18 subjects with schizophrenia and 18 subjects with major depression. Along with rivalry rate, the predominance of each of the rivaling images was assessed, as was the distribution of normalized rivalry intervals. Results. The bipolar group demonstrated significantly slower rivalry than the control, schizophrenia and major depression groups. The schizophrenia and major depression groups did not differ significantly from the control group. Predominance values did not differ according to diagnosis and the distribution of normalized rivalry intervals was well described by a gamma function in all groups. Conclusions. The results provide further evidence that binocular rivalry is slow in bipolar disorder and demonstrate that rivalry predominance and the distribution of normalized rivalry intervals are not abnormal in bipolar disorder. It is also shown by comparison with previous work, that high strength stimuli more effectively distinguish bipolar from control subjects than low strength stimuli. The data on schizophrenia and major depression suggest the need for large-scale specificity trials. Further study is also required to assess genetic and pathophysiological factors as well as the potential effects of state, medication, and clinical and biological subtypes.
Keyword Psychiatry
Psychology, Clinical
Retinal Rivalry
Reversible Perspective
Optokinetic Nystagmus
Stochastic Properties
Perceptual Rivalry
Visual Awareness
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2004 Higher Education Research Data Collection
School of Psychology Publications
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Citation counts: TR Web of Science Citation Count  Cited 30 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 35 times in Scopus Article | Citations
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Created: Wed, 15 Aug 2007, 02:38:44 EST