Age-at-first-registration and heterogeneity in affective psychoses

Welham, J. L., Thomis, R. and McGrath, J. J. (2003) Age-at-first-registration and heterogeneity in affective psychoses. Australian And New Zealand Journal of Psychiatry, 37 1: 66-69. doi:10.1046/j.1440-1614.2003.01106.x

Author Welham, J. L.
Thomis, R.
McGrath, J. J.
Title Age-at-first-registration and heterogeneity in affective psychoses
Journal name Australian And New Zealand Journal of Psychiatry   Check publisher's open access policy
ISSN 0004-8674
Publication date 2003
Sub-type Article (original research)
DOI 10.1046/j.1440-1614.2003.01106.x
Volume 37
Issue 1
Start page 66
End page 69
Total pages 4
Editor Sidney Bloch
Place of publication Australia
Publisher Blackwell Publishing Asia
Collection year 2003
Language eng
Subject C1
321021 Psychiatry
730211 Mental health
Abstract Background: Previous research into age of onset in affective disorders has produced conflicting results. This paper examines the influence of heterogeneity on the age-at-first-registration distribution for the ICD-9 diagnostic group 'affective psychosis'. Method: For 1979-1991, data for age-at-first-registration for 4985 individuals diagnosed with affective psychosis (ICD-9 296.x) were extracted from a name-linked mental health register. These data were divided into (i) '296.1 only', a category used to code unipolar depression (males = 700; females = 1321); and (ii) '296 other', all 296 cases other than 296.1 (males = 1280; females = 1684). Inception rates for each 5-year age division were adjusted for the background population age-structure as a rate per 100 000 population. Results: The age-at-first-registration distribution for affective psychosis has a wide age range, with women outnumbering men. There is a near-linear increase in inception rates for both men and women with 296.1 only, while the bulk of those with affective psychoses (296 other) have an inverted U-shaped age distribution. Males have an earlier modal age-at-first-registration for 296 other compared to females. Conclusion: The heterogeneity in terms of subtypes and sex in affective psychosis clouds the interpretation of age-at-first-registration. Separating those with unipolar psychotic depression from other subclassifications and differentiating by sex may provide clues to factors that precipitate the onset of affective psychosis.
Keyword Psychiatry
Affective Psychosis
Bipolar Disorder
Manic Depression
Sex Differences
Bipolar Affective-illness
Major Depression
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2004 Higher Education Research Data Collection
School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 4 times in Thomson Reuters Web of Science Article | Citations
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Created: Wed, 15 Aug 2007, 02:16:54 EST