Age-at-first-registration and heterogeneity in affective psychoses

Welham, J. L., Thomis, R. and McGrath, J. J. (2003) Age-at-first-registration and heterogeneity in affective psychoses. Australian And New Zealand Journal of Psychiatry, 37 1: 66-69. doi:10.1046/j.1440-1614.2003.01106.x


Author Welham, J. L.
Thomis, R.
McGrath, J. J.
Title Age-at-first-registration and heterogeneity in affective psychoses
Journal name Australian And New Zealand Journal of Psychiatry   Check publisher's open access policy
ISSN 0004-8674
Publication date 2003
Sub-type Article (original research)
DOI 10.1046/j.1440-1614.2003.01106.x
Volume 37
Issue 1
Start page 66
End page 69
Total pages 4
Editor Sidney Bloch
Place of publication Australia
Publisher Blackwell Publishing Asia
Collection year 2003
Language eng
Subject C1
321021 Psychiatry
730211 Mental health
Abstract Background: Previous research into age of onset in affective disorders has produced conflicting results. This paper examines the influence of heterogeneity on the age-at-first-registration distribution for the ICD-9 diagnostic group 'affective psychosis'. Method: For 1979-1991, data for age-at-first-registration for 4985 individuals diagnosed with affective psychosis (ICD-9 296.x) were extracted from a name-linked mental health register. These data were divided into (i) '296.1 only', a category used to code unipolar depression (males = 700; females = 1321); and (ii) '296 other', all 296 cases other than 296.1 (males = 1280; females = 1684). Inception rates for each 5-year age division were adjusted for the background population age-structure as a rate per 100 000 population. Results: The age-at-first-registration distribution for affective psychosis has a wide age range, with women outnumbering men. There is a near-linear increase in inception rates for both men and women with 296.1 only, while the bulk of those with affective psychoses (296 other) have an inverted U-shaped age distribution. Males have an earlier modal age-at-first-registration for 296 other compared to females. Conclusion: The heterogeneity in terms of subtypes and sex in affective psychosis clouds the interpretation of age-at-first-registration. Separating those with unipolar psychotic depression from other subclassifications and differentiating by sex may provide clues to factors that precipitate the onset of affective psychosis.
Keyword Psychiatry
Affective Psychosis
Age-of-onset
Bipolar Disorder
Manic Depression
Sex Differences
Bipolar Affective-illness
Affective-disorders
Sex-differences
Major Depression
Old-age
Onset
Schizophrenia
Rates
Epidemiology
Childbearing
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2004 Higher Education Research Data Collection
School of Medicine Publications
 
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Created: Wed, 15 Aug 2007, 02:16:54 EST