Physical and mental health: Changes during menopause transition

Mishra, Gita D., Brown, Wendy J. and Dobson, Annette J. (2003) Physical and mental health: Changes during menopause transition. Quality of Life Research, 12 4: 405-412. doi:10.1023/A:1023421128141

Author Mishra, Gita D.
Brown, Wendy J.
Dobson, Annette J.
Title Physical and mental health: Changes during menopause transition
Journal name Quality of Life Research   Check publisher's open access policy
ISSN 0962-9343
Publication date 2003-06
Sub-type Article (original research)
DOI 10.1023/A:1023421128141
Volume 12
Issue 4
Start page 405
End page 412
Total pages 8
Editor N. K. Aaronson
Place of publication Dordrecht, Netherlands
Publisher Kluwer
Collection year 2003
Language eng
Subject 321299 Public Health and Health Services not elsewhere classified
730201 Women's health
Formatted abstract
To measure changes in physical and mental health in six groups of women defined by menopausal status or use of hormone replacement therapy (HRT).

Longitudinal study with 2 years follow-up.

Eight thousand six hundred and twenty three women participating in the Australian Longitudinal Study on Women's Health, aged 45-50 years in 1996.

Main outcome measures:

Changes in the eight dimensions of the Short Form General Health Survey (SF-36) adjusted for baseline scores, lifestyle, behavioural and demographic factors.

At baseline, mean scores for five of the eight dimensions of the SF-36 were highest ( indicating better state of health or well-being) in premenopausal women. There were declines ( that is, worsening health) in the SF-36 dimensions in most groups of women. Declines were largest in physical functioning ( adjusted mean change of) 4.9, standard error ( SE) 0.7) and physical role limitation (-5.7, SE: 1.3) in women who remained peri-menopausal throughout the study period and in women taking HRT at the time of either survey ( physical functioning:) 5.3 ( 0.7), role physical limitation:) 7.5 ( 1.2)). They were smallest in women who remained pre-menopausal ( physical functioning:) 3.2 ( 0.7); role physical limitation:) 2.1 ( 1.1)).

Physical aspects of general health and well-being decline during the menopausal transition. Sensitive measures and careful analysis are needed to understand why these changes are worse for peri-menopausal women and those taking HRT.
Keyword Health Care Sciences & Services
Public, Environmental & Occupational Health
Australian Women
Aged Women
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

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Created: Wed, 15 Aug 2007, 01:31:16 EST