The distribution and morphological characteristics of serotonergic cells in the brain of monotremes

Manger, PR, Fahringer, HM, Pettigrew, JD and Siegel, JM (2002) The distribution and morphological characteristics of serotonergic cells in the brain of monotremes. Brain Behavior And Evolution, 60 5: 315-332. doi:10.1159/000067194


Author Manger, PR
Fahringer, HM
Pettigrew, JD
Siegel, JM
Title The distribution and morphological characteristics of serotonergic cells in the brain of monotremes
Journal name Brain Behavior And Evolution   Check publisher's open access policy
ISSN 0006-8977
Publication date 2002
Sub-type Article (original research)
DOI 10.1159/000067194
Volume 60
Issue 5
Start page 315
End page 332
Total pages 18
Place of publication Switzerland
Publisher S. Karger AG
Collection year 2002
Language eng
Subject C1
320702 Central Nervous System
780105 Biological sciences
0603 Evolutionary Biology
Abstract The distribution and cellular morphology of serotonergic neurons in the brain of two species of monotremes are described. Three clusters of serotonergic neurons were found: a hypothalamic cluster, a cluster in the rostral brainstem and a cluster in the caudal brainstem. Those in the hypothalamus consisted of two groups, the periventricular hypothalamic organ and the infundibular recess, that were intimately associated with the ependymal wall of the third ventricle. Within the rostral brainstem cluster, three distinct divisions were found: the dorsal raphe nucleus (with four subdivisions), the median raphe nucleus and the cells of the supralemniscal region. The dorsal raphe was within and adjacent to the periaqueductal gray matter, the median raphe was associated with the midline ventral to the dorsal raphe, and the cells of the supralemniscal region were in the tegmentum lateral to the median raphe and ventral to the dorsal raphe. The caudal cluster consisted of three divisions: the raphe obscurus nucleus, the raphe pallidus nucleus and the raphe magnus nucleus. The raphe obscurus nucleus was associated with the dorsal midline at the caudal-most part of the medulla oblongata. The raphe pallidus nucleus was found at the ventral midline of the medulla around the inferior olive. Raphe magnus was associated with the midline of the medulla and was found rostral to both the raphe obscurus and raphe pallidus. The results of our study are compared in an evolutionary context with those reported for other mammals and reptiles. Copyright (C) 2002 S. Karger AG, Basel.
Keyword Behavioral Sciences
Neurosciences
Mammals
Monotremes
Platypus
Echidna
Serotonin
Evolution
Sleep
Monoamine-containing Neurons
Stem
System
Cat
Atlas
Organization
Fluorescence
Rodent
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collection: Queensland Brain Institute Publications
 
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Created: Tue, 14 Aug 2007, 19:02:13 EST