Combining the analyses of introgressive hybridisation and linkage mapping to investigate the genetic architecture of population divergence in the lake whitefish (Coregonus clupeaformis, Mitchill)

Rogers, SM, Campbell, D, Baird, SJE, Danzmann, RG and Bernatchez, L (2001) Combining the analyses of introgressive hybridisation and linkage mapping to investigate the genetic architecture of population divergence in the lake whitefish (Coregonus clupeaformis, Mitchill). Genetica, 111 1-3: 25-41. doi:10.1023/A:1013773600304


Author Rogers, SM
Campbell, D
Baird, SJE
Danzmann, RG
Bernatchez, L
Title Combining the analyses of introgressive hybridisation and linkage mapping to investigate the genetic architecture of population divergence in the lake whitefish (Coregonus clupeaformis, Mitchill)
Journal name Genetica   Check publisher's open access policy
ISSN 0016-6707
Publication date 2001
Sub-type Article (original research)
DOI 10.1023/A:1013773600304
Volume 111
Issue 1-3
Start page 25
End page 41
Total pages 17
Place of publication Netherlands
Publisher Kluwer Academic Publishers
Collection year 2002
Language eng
Subject C1
300701 Physiology and Genetics
779903 Living resources (flora and fauna)
Abstract Adaptation and reproductive isolation, the engines of biological diversity, are still elusive when discussing the genetic bases of speciation. Namely, the number of genes and magnitude of selection acting positively or negatively on genomic traits implicated in speciation is contentious. Here, we describe the first steps of an ongoing research program aimed at understanding the genetic bases of population divergence and reproductive isolation in the lake whitefish (Coregonus clupeaformis). A preliminary linkage map originating from a hybrid cross between dwarf and normal ecotypes is presented, whereby some of the segregating AFLP markers were found to be conserved among natural populations. Maximum-likelihood was used to estimate hybrid indices from non-diagnostic markers at 998 AFLP loci. This allowed identification of the most likely candidate loci that have been under the influence of selection during the natural hybridisation of whitefish originating from different glacial races. As some of these loci could be identified on the linkage map, the possibility that selection of traits in natural populations may eventually be correlated to specific chromosomal regions was demonstrated. The future prospects and potential of these approaches to elucidate the genetic bases of adaptation and reproductive isolation among sympatric ecotypes of lake whitefish is discussed.
Keyword Genetics & Heredity
Adaptive Radiation
Aflp
Coregonus Clupeaformis
Hybrid Index
Introgression
Linkage Mapping
Maximum Likelihood
Speciation
Mitochondrial-dna
Hybrid Zones
Reproductive Isolation
Monkeyflowers Mimulus
Ecological Speciation
Evolutionary Biology
Sympatric Speciation
Floral Traits
Map
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Biological Sciences Publications
 
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Created: Tue, 14 Aug 2007, 17:35:58 EST