Serrated adenoma of the colorectum

Jass, J. R. (2002) Serrated adenoma of the colorectum. Current Diagnostic Pathology, 8 1: 42-49. doi:10.1054/cdip.2001.0094


Author Jass, J. R.
Title Serrated adenoma of the colorectum
Journal name Current Diagnostic Pathology   Check publisher's open access policy
ISSN 0968-6053
Publication date 2002
Sub-type Article (original research)
DOI 10.1054/cdip.2001.0094
Volume 8
Issue 1
Start page 42
End page 49
Total pages 8
Editor C. S. Herrington
K. Henry
R. N. M. MacSween
Place of publication United Kingdom
Publisher Elsevier Science
Collection year 2002
Language eng
Subject C1
321006 Gastroenterology and Hepatology
730108 Cancer and related disorders
1103 Clinical Sciences
Abstract An understanding of the pathology and natural history of serrated adenoma of the colorectum has emerged slowly and comparatively recently. In this review, hyperplastic polyps, admixed polyps and serrated adenomas are conceived as a continuum of serrated polyps. Mechanisms underlying the expression of serrated morphology are outlined. The demographic, macroscopic and microscopic features of serrated adenoma are presented but it is stressed that the distinction from other epithelial polyps may not always be straightforward. Molecular studies point to heterogeneity within the serrated pathway and among conditions encompassed by the term serrated polyposis. Management of serrated adenoma is discussed but the need for further research is emphasized. The importance of serrated adenoma as a precancerous lesion has been underestimated. © 2002 Elsevier Science Ltd.
Keyword Colorectum
Hyperplastic polyp
Polyposis
Serrated adenoma
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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Created: Tue, 14 Aug 2007, 17:06:03 EST