The complete genome of the crenarchaeon sulfolobus solfataricus P2

She, Qunxin, Singh, Rama K., Confalonieri, Fabrice, Zivanovic, Yvan, Allard, Ghislaine, Awayez, Mariana J., Chan-Weiher, Christina C.-Y., Clausen, Ib Groth, Curtis, Bruce A., De Moors, Anick, Erauso, Gael, Fletcher, Cynthia, Gordon, Paul M. K., Heikamp-de Jong, Ineke, Jeffries, Alex C., Kozera, Catherine J., Medina, Nadine, Peng, Xu, Thi-Ngoc, Hoa Phan, Redder, Peter, Schenk, Margaret E., Theriault, Cynthia, Tolstrup, Niels, Charlebois, Robert L., Doolittle, W. Ford, Duguet, Michel, Gaasterland, Terry, Garrett, Roger A., Ragan, Mark A., Sensen, Christoph W. and Van der Oost, John (2001) The complete genome of the crenarchaeon sulfolobus solfataricus P2. Proceedings of the National Academy of Sciences, 98 14: 7835-7840. doi:10.1073/pnas.141222098

Author She, Qunxin
Singh, Rama K.
Confalonieri, Fabrice
Zivanovic, Yvan
Allard, Ghislaine
Awayez, Mariana J.
Chan-Weiher, Christina C.-Y.
Clausen, Ib Groth
Curtis, Bruce A.
De Moors, Anick
Erauso, Gael
Fletcher, Cynthia
Gordon, Paul M. K.
Heikamp-de Jong, Ineke
Jeffries, Alex C.
Kozera, Catherine J.
Medina, Nadine
Peng, Xu
Thi-Ngoc, Hoa Phan
Redder, Peter
Schenk, Margaret E.
Theriault, Cynthia
Tolstrup, Niels
Charlebois, Robert L.
Doolittle, W. Ford
Duguet, Michel
Gaasterland, Terry
Garrett, Roger A.
Ragan, Mark A.
Sensen, Christoph W.
Van der Oost, John
Title The complete genome of the crenarchaeon sulfolobus solfataricus P2
Formatted title
The complete genome of the crenarchaeon sulfolobus solfataricus P2
Journal name Proceedings of the National Academy of Sciences   Check publisher's open access policy
ISSN 0027-8424
Publication date 2001-07-03
Sub-type Article (original research)
DOI 10.1073/pnas.141222098
Volume 98
Issue 14
Start page 7835
End page 7840
Total pages 6
Place of publication Washington, DC, United States
Publisher National Academy of Sciences
Collection year 2001
Language eng
Subject C1
270202 Genome Structure
780105 Biological sciences
Formatted abstract
The genome of the crenarchaeon Sulfolobus solfataricus P2 contains 2,992,245 bp on a single chromosome and encodes 2.977 proteins and many RNAs. One-third of the encoded proteins have no detectable homologs in other sequenced genomes. Moreover, 40% appear to be archaeal-specific, and only 12% and 2.3% are shared exclusively with bacteria and eukarya, respectively. The genome shows a high level of plasticity with 200 diverse insertion sequence elements, many putative nonautonomous mobile elements, acid evidence of integrase-mediated insertion events. There a re also ion g clusters of regularly spaced tandem repeats. Different transfer systems are used for the uptake of inorganic and organic solutes, and a wealth of intracellular and extracellular proteases, sugar, and sulfur metabolizing enzymes are encoded, as well as enzymes of the central metabolic pathways and motility proteins. The major metabolic electron carrier is not NADH as in bacteria and eukarya but probably ferredoxin. The essential components required for DNA replication, DNA repair and recombination, the cell cycle, transcriptional initiation and translation, but not DNA folding, show a strong eukaryal character with many archaeal-specific features. The results illustrate major differences between crenarchaea and euryarchaea, especially for their DNA replication mechanism and cell cycle processes and their translational apparatus.
Keyword DNA-binding proteins
Extremely thermophilic archaeon
Dependent RNA-polymerases
Hyperthermophilic archaeon
Thermoacidophilic archaebacterium
Reverse gyrase
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: School of Information Technology and Electrical Engineering Publications
Institute for Molecular Bioscience - Publications
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 551 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 542 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 14 Aug 2007, 16:01:50 EST