Carbohydrate-based templates for synthetic vaccines and drug delivery

McGeary, R. P., Jablonkai, I. and Toth, I. (2001) Carbohydrate-based templates for synthetic vaccines and drug delivery. Tetrahedron, 57 41: 8733-8742. doi:10.1016/S0040-4020(01)00852-3


Author McGeary, R. P.
Jablonkai, I.
Toth, I.
Title Carbohydrate-based templates for synthetic vaccines and drug delivery
Journal name Tetrahedron   Check publisher's open access policy
ISSN 0040-4020
Publication date 2001
Sub-type Article (original research)
DOI 10.1016/S0040-4020(01)00852-3
Volume 57
Issue 41
Start page 8733
End page 8742
Total pages 10
Place of publication Oxford, UK
Publisher Pergamon-Elsevier Science
Collection year 2001
Language eng
Subject C1
320501 Pharmaceutical Sciences and Pharmacy
670403 Treatments (e.g. chemicals, antibiotics)
Abstract Methyl tetra-O-allyl, and tetra-O-[2-(tetrahydro-2H-pyranyl)oxy.-3-oxapentyl glucosides, and tetra-O-(cyanoethyl)galactosyl azide were converted into derivatives containing linkers with terminal carboxylic acid functionalities at the anomeric position and bearing four arms with phthaloyl- or BOC-protected terminal amino groups. These molecules were suitable for use in solid-phase peptide synthesis and for the preparation of dendrimers, containing multiple copies of peptides. (C) 2001 Elsevier Science Ltd. All rights reserved.
Keyword Chemistry, Organic
Synthetic Vaccines
Carbohydrates
Solid-phase Synthesis
Adjuvants/carriers
Design
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Pharmacy Publications
 
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