The toxins of Lyngbya majuscula and their human and ecological health effects

Osborne, Nicholas J. T., Webb, Penny M. and Shaw, Glen R. (2001) The toxins of Lyngbya majuscula and their human and ecological health effects. Environment International, 27 5: 381-392. doi:10.1016/S0160-4120(01)00098-8


Author Osborne, Nicholas J. T.
Webb, Penny M.
Shaw, Glen R.
Title The toxins of Lyngbya majuscula and their human and ecological health effects
Journal name Environment International   Check publisher's open access policy
ISSN 0160-4120
1873-6750
Publication date 2001
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/S0160-4120(01)00098-8
Volume 27
Issue 5
Start page 381
End page 392
Total pages 12
Place of publication Oxford, UK
Publisher Pergamon-Elsevier Science Ltd
Collection year 2001
Language eng
Subject C1
321299 Public Health and Health Services not elsewhere classified
730210 Environmental health
Abstract Lyngbya majuscula is a benthic filamentous marine cyanobacterium, which in recent years appears to have been increasing in frequency and size of blooms in Moreton Bay, Queensland. It has a worldwide distribution throughout the tropics and subtropics in water to 30m. It has been found to contain a variety of chemicals that exert a range of biological effects, including skin, eye and respiratory irritation. The toxins lyngbyatoxin A and debromoaplysiatoxin appear to give the most widely witnessed biological effects in relation to humans, and experiments involving these two toxins show the formation of acute dermal lesions. Studies into the epidemiology of the dermatitic, respiratory and eye effects of the toxins of this organism are reviewed and show that Lyngbya induced dermatitis has occurred in a number of locations. The effects of aerosolised Lyngbya in relation to health outcomes were also reported. Differential effects of bathing behaviour after Lyngbya exposure were examined in relation to the severity of health outcomes. The potential for Lyngbya to exhibit differential toxicologies due to the presence of varying proportions of a range of toxins is also examined. This paper reviews the present state of knowledge on the effects of Lyngbya majuscula on human health, ecosystems and human populations during a toxic cyanobacterial bloom. The potential exists for toxins from Lyngbya majuscula affecting ecological health and in particular marine reptiles. (C) 2001 Elsevier Science Ltd. All rights reserved.
Keyword Environmental Sciences
Lyngbya Majuscula
Cyanobacterium
Epidemiology
Toxin
Dermatitis
Marine
Blue-green-alga
Oncogene-induced Transformation
Protein-kinase-c
Tumor Promoters
Marine Cyanobacteria
Gracilaria-coronopifolia
Secondary Metabolites
Biological-activity
Absolute-configuration
Indole Alkaloids
Q-Index Code C1

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: School of Public Health Publications
National Research Centre for Environmental Toxicology Publications
 
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Created: Tue, 14 Aug 2007, 15:41:54 EST