Oral Colonization of Streptococcus mutans in Six-month-old Predentate Infants

Wan, A. K. L., Seow, W. K., Purdie, D. M., Bird, P. S., Walsh, L. J. and Tudehope, D. I. (2001) Oral Colonization of Streptococcus mutans in Six-month-old Predentate Infants. Journal of Dental Research, 80 12: 2060-2065. doi:10.1177/00220345010800120701

Author Wan, A. K. L.
Seow, W. K.
Purdie, D. M.
Bird, P. S.
Walsh, L. J.
Tudehope, D. I.
Title Oral Colonization of Streptococcus mutans in Six-month-old Predentate Infants
Journal name Journal of Dental Research   Check publisher's open access policy
ISSN 0022-0345
Publication date 2001-12
Sub-type Article (original research)
DOI 10.1177/00220345010800120701
Volume 80
Issue 12
Start page 2060
End page 2065
Total pages 6
Editor Mark C. Herzberg
Place of publication Chicago, Ill., U.S.A.
Publisher American Association for Dental Research
Collection year 2001
Language eng
Subject C1
320899 Dentistry not elsewhere classified
730112 Oro-dental and disorders
Abstract We hypothesize that S. mutans colonization occurs more frequently in pre-term children due to their relative immaturity. In this study of 172 predentate, six-month-old infants, we found that 50% of pre-term and 60% of full-term children harbored S. mutans. The colonization was confirmed by repeat sampling. Although there were minor differences, factors associated with S. mutans infection in pre-term and full-term infants were generally similar. In both groups, increased frequency of sugar was ranked the most important factor (p < 0.001), followed by breast-feeding (p < 0.001), and habits which allowed saliva transfer from mother to infant (p < 0.01). By contrast, non-colonization of S. mutans was associated with multiple courses of antibiotics (p < 0.001). Compared with pre-term children, there were higher percentages of full-term who had night feedings and consumed sugar during sleep times. Mothers with infected infants had S. mutans levels > 5 x 10(5) CFU/mL saliva (p < 0.001), poorer oral hygiene,, more periodontal disease, and lower socio-economic status (P < 0.02) and snacked frequently (p < 0.001), compared with mothers with non-infected infants.
Keyword Dentistry, Oral Surgery & Medicine
Streptococcus Mutans
Early Childhood Caries
Early-childhood Caries
Initial Acquisition
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Dentistry Publications
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Created: Tue, 14 Aug 2007, 15:14:28 EST