Serrated route to colorectal cancer: back street or super highway?

Jass, Jeremy R. (2001) Serrated route to colorectal cancer: back street or super highway?. Journal of Pathology, 193 3: 283-285. doi:10.1002/1096-9896(200103)193:3<283::AID-PATH799>3.0.CO;2-9


Author Jass, Jeremy R.
Title Serrated route to colorectal cancer: back street or super highway?
Journal name Journal of Pathology   Check publisher's open access policy
ISSN 0022-3417
Publication date 2001-03
Sub-type Editorial
DOI 10.1002/1096-9896(200103)193:3<283::AID-PATH799>3.0.CO;2-9
Volume 193
Issue 3
Start page 283
End page 285
Total pages 3
Place of publication United Kingdom
Publisher John Wiley & Sons Ltd
Collection year 2001
Language eng
Subject C1
321006 Gastroenterology and Hepatology
730108 Cancer and related disorders
Abstract Morphological and molecular studies are beginning to distinguish separate evolutionary pathways for colorectal cancer, The serrated pathway encompassing hyperplastic aberrant crypt foci, hyperplastic polyps. mixed polyps, and serrated adenoma is increasingly being linked with genetic alterations, including DNA methylation, DNA microsatellite instability, Ii-ras mutation, and loss of chromosome Ip, The importance of the serrated pathway has been underestimated in terms of its frequency and potential for rapid progression, Copyright (C) 2001 John Wiley & Sons, Ltd.
Keyword Pathology
Colorectum
Serrated
Hyperplastic
Polyp
Carcinoma
Microsatellite Instability
Methylation
Aberrant Crypt Foci
Hyperplastic Polyposis
Mutator Pathways
Adenomas
Progression
Colon
Q-Index Code C1

Document type: Journal Article
Sub-type: Editorial
Collection: School of Medicine Publications
 
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Created: Tue, 14 Aug 2007, 14:56:27 EST