Performance on tests sensitive to impaired executive ability in schizophrenia, mania and well controls: acute and subacute phases

McGrath, J, Scheldt, S, Welham, J and Clair, A (1997) Performance on tests sensitive to impaired executive ability in schizophrenia, mania and well controls: acute and subacute phases. Schizophrenia Research, 26 2-3: 127-137. doi:10.1016/S0920-9964(97)00070-4


Author McGrath, J
Scheldt, S
Welham, J
Clair, A
Title Performance on tests sensitive to impaired executive ability in schizophrenia, mania and well controls: acute and subacute phases
Journal name Schizophrenia Research   Check publisher's open access policy
ISSN 0920-9964
Publication date 1997-01-01
Sub-type Article (original research)
DOI 10.1016/S0920-9964(97)00070-4
Volume 26
Issue 2-3
Start page 127
End page 137
Total pages 11
Language eng
Abstract Aims: To compare the performance of schizophrenia, mania and well control groups on tests sensitive to impaired executive ability, and to assess the within-group stability of these measures across the acute and subacute phases of psychoses. Method: Recently admitted patients with schizophrenia (n=36), mania (n=18) and a well control group (n=20) were assessed on two occasions separated by 4 weeks. Tests included: the Controlled Oral Word Association Test, the Stroop Test, the Wisconsin Card Sort Test, and the Trail Making Test. Results: The two patient groups were significantly impaired on the Stroop Test at both time points compared to the control group. Significant group differences were also found for the Trail Making Test at Time 1 and for the Wisconsin Card Sort Test at Time 2. When controlled for practice effect, significant improvements over time were found on the Stroop and Trail Making tests in the schizophrenia group and on WCST Categories Achieved in the mania group. Discussion: Compared to controls, the patient groups were impaired on measures related to executive ability. The pattern of improvement on test scores between the acute and subacute phases differed between patients with schizophrenia versus patients with mania. (C) 1997 Elsevier Science B.V.
Keyword Psychiatry
Schizophrenia
Mania
Executive Ability
Neuropsychological Test-performance
Card Sorting Test
Prefrontal Dysfunction
Negative Symptoms
Follow-up
Clozapine
Stability
Disorder
Deficits
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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Created: Tue, 14 Aug 2007, 02:59:17 EST