A controlled trial comparing the efficacy of rice-based and hypotonic glucose oral rehydration solutions in infants and young children with gastroenteritis

Wall, CR, Swanson, CE and Cleghorn, GJ (1997) A controlled trial comparing the efficacy of rice-based and hypotonic glucose oral rehydration solutions in infants and young children with gastroenteritis. Journal of Gastroenterology And Hepatology, 12 1: 24-28.


Author Wall, CR
Swanson, CE
Cleghorn, GJ
Title A controlled trial comparing the efficacy of rice-based and hypotonic glucose oral rehydration solutions in infants and young children with gastroenteritis
Journal name Journal of Gastroenterology And Hepatology   Check publisher's open access policy
Publication date 1997
Sub-type Article
DOI 10.1111/j.1440-1746.1997.tb00340.x
Volume number 12
Issue number 1
ISSN 0815-9319
Start page 24
End page 28
Total pages 5
Language eng
Abstract A prospective randomized trial was conducted to compare the efficacy of a rice-based oral rehydration solution (ORS) with glucose ORS in infants and children under 5 years of age with acute diarrhoea and mild to moderate dehydration (<10%). One hundred children presenting to a large metropolitan teaching hospital were eligible for entry to the study and were randomized to receive rice ORS or glucose ORS. Outcome measures were stool output (SO), duration of illness (DD) and recovery time to introduction of other fluids (RTF) and diet (RTD). Significant differences were found for all outcome measures in favour of the rice ORS group. Mean SO was lower (160 vs 213 mt; P<0.02), mean DD was reduced (17.3 vs 24.3 h; P = 0.03) and median RTF was decreased (12.7 vs 18.1 h; P< 0.001) in the rice ORS group compared with the glucose ORS group. The median rime to introduction of diet and mean length of hospital stay showed similar significant reductions. Our study has shown rice ORS to be an acceptable alternative to glucose ORS in young children and have shown that it is significantly more effective in reducing the course of diarrhoeal illness and the time taken to return to normal drinking and eating habits.
Keyword Gastroenterology & Hepatology
Acute Gastroenteritis
Dehydration
Oral Rehydration Solutions
Electrolyte Solution
Diarrhea
Absorption
Therapy
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article
Collection: School of Medicine Publications
 
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Created: Mon, 13 Aug 2007, 16:42:14 EST