Compensation for obesity-induced insulin resistance in dogs: Causal web analysis of the associations of leptin and GLP-1.

Verkest, K. R., Fleeman, L. M., Rand, J. S., Morton, J. M. and Ishioka, K. (2006). Compensation for obesity-induced insulin resistance in dogs: Causal web analysis of the associations of leptin and GLP-1.. In: Journal of Veterinary Internal Medicine. 24th Annual ACVIM Forum, Annual Conference of the American College of Veterinary Internal Medicine, American College of Veterinary Internal Medicine, Louisville, KY, (727-727). 31 May - 3 June 2006. doi:10.1111/j.1939-1676.2006.tb02919.x


Author Verkest, K. R.
Fleeman, L. M.
Rand, J. S.
Morton, J. M.
Ishioka, K.
Title of paper Compensation for obesity-induced insulin resistance in dogs: Causal web analysis of the associations of leptin and GLP-1.
Conference name 24th Annual ACVIM Forum, Annual Conference of the American College of Veterinary Internal Medicine
Conference location American College of Veterinary Internal Medicine, Louisville, KY
Conference dates 31 May - 3 June 2006
Proceedings title Journal of Veterinary Internal Medicine   Check publisher's open access policy
Journal name Journal of Veterinary Internal Medicine   Check publisher's open access policy
Place of Publication Hoboken, N. J.
Publisher Wiley
Publication Year 2006
DOI 10.1111/j.1939-1676.2006.tb02919.x
Open Access Status DOI
ISSN 0891-6640
Volume 20
Issue 3
Start page 727
End page 727
Total pages 1
Language eng
Abstract/Summary Obesity affects aspects of glucose homeostasis such as insulin secretion and insulin sensitivity. Hormones secreted by adipocytes like leptin mediate the metabolic consequences of obesity. Incretin hormones like glucagon-like peptide-1 (GLP-1) increase insulin secretion in response to changes in blood glucose concentration and have been proposed to regulate insulin secretion in fasting, overweight dogs. The aim of this study was to examine hormonal mechanisms by which adiposity alters glucose homeostasis, plasma insulin concentration, and insulin sensitivity in spontaneously overweight dogs.
Subjects 070704 Veterinary Epidemiology
Keyword Veterinary Sciences
Q-Index Code EX
Q-Index Status Provisional Code
Institutional Status Unknown
Additional Notes Research Abstract Program of the 24th Annual ACVIM Forum

 
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Created: Mon, 13 Aug 2007, 16:13:49 EST