Benzothiazole serivatives as potential anti-infective agents

Sharma, Prabodh Chander, Bansal, Kushal Kumar, Deep, Aakash and Pathak, Meenakshi (2017) Benzothiazole serivatives as potential anti-infective agents. Current Topics in Medicinal Chemistry, 17 2: 208-237. doi:10.2174/1568026616666160530152546


Author Sharma, Prabodh Chander
Bansal, Kushal Kumar
Deep, Aakash
Pathak, Meenakshi
Title Benzothiazole serivatives as potential anti-infective agents
Journal name Current Topics in Medicinal Chemistry   Check publisher's open access policy
ISSN 1568-0266
1873-4294
Publication date 2017-01-01
Sub-type Critical review of research, literature review, critical commentary
DOI 10.2174/1568026616666160530152546
Open Access Status Not yet assessed
Volume 17
Issue 2
Start page 208
End page 237
Total pages 30
Place of publication Bussum, Netherlands
Publisher Bentham Science Publishers
Collection year 2018
Language eng
Formatted abstract
Background: Severity of microbial infections and escalating resistance towards antibiotics has created a deep necessity for discovery of novel anti-infective agents. Heterocyclic chemistry of benzothiazole has become one of the most prolific areas in the field of drug discovery and development that has attracted great attention in recent time due to its increasing importance in the field of pharmaceuticals.

Method: The importance of benzothiazole and derivatives as potential antimicrobial agents has been well established and a large number of papers have been published in this regard.

Result: The present communication is an earnest attempt to review the chemistry, synthetic aspects including click chemistry and antimicrobial activities of benzothiazole derivatives reported in recent scientific literature.

Conclusion: The scientific information of this manuscript may be worthwhile in encouraging the prospective researchers working on this heterocyclic scaffold.
Keyword Benzothiazole
Synthesis
Click Chemistry
Anti-infective activity
Chemotherapy
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: HERDC Pre-Audit
School of Pharmacy Publications
 
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