Anxiety, depression and quality of life in people with pancreatic cancer and their carers

Janda, Monika, Neale, Rachel E., Klein, Kerenaftali, O'Connell, Dianne L., Gooden, Helen, Goldstein, David, Merrett, Neil D., Wyld, David K., Rowlands, Ingrid J. and Beesley, Vanessa L. (2017) Anxiety, depression and quality of life in people with pancreatic cancer and their carers. Pancreatology, . doi:10.1016/j.pan.2017.01.008


Author Janda, Monika
Neale, Rachel E.
Klein, Kerenaftali
O'Connell, Dianne L.
Gooden, Helen
Goldstein, David
Merrett, Neil D.
Wyld, David K.
Rowlands, Ingrid J.
Beesley, Vanessa L.
Title Anxiety, depression and quality of life in people with pancreatic cancer and their carers
Journal name Pancreatology   Check publisher's open access policy
ISSN 1424-3911
1424-3903
Publication date 2017-01-20
Year available 2017
Sub-type Article (original research)
DOI 10.1016/j.pan.2017.01.008
Open Access Status Not yet assessed
Total pages 1
Place of publication Amsterdam, Netherlands
Publisher Elsevier
Collection year 2018
Language eng
Formatted abstract
Background

People with pancreatic cancer have high levels of anxiety and depression and reduced quality of life (QoL), but few studies have assessed these outcomes for patient-carer dyads. We therefore investigated these issues in an Australian population-based study.

Methods

Patients with pancreatic cancer (n = 136) and many of their carers (n = 84) completed the Hospital Anxiety and Depression Scale (HADS) and Functional Assessment of Cancer Therapy QoL questionnaire at a median of three months after diagnosis. Overall QoL and well-being subscales (physical, social, emotional, functional) were compared with general population norms. Intraclass correlation coefficients were used to compare anxiety, depression and QoL scores of patients and their respective carers.

Results

Fifteen percent of patients and 39% of carers had HADS scores indicative of anxiety and 15% of patients and 14% of carers of depression, respectively. Overall, 70% of patients and 58% of carers had QoL scores below the Queensland population average. Patients' anxiety, depression, overall QoL, social, emotional and functional wellbeing scores were significantly related to those scores in their carers. Among patients and carers, accessing psychological help was associated with elevated anxiety. Not receiving chemotherapy was associated with elevated depression among patients and younger age was associated with poorer outcomes in carers.

Conclusions

More carers had symptoms of anxiety than patients with pancreatic cancer, but symptoms of depression were similarly common in patients and carers. Further research is needed to assess whether interventions to reduce patients' distress could also improve QoL among carers, or whether carer-focussed interventions are required.
Keyword Pancreatic neoplasms
Quality of life
Anxiety
Depression
Patients
Carers
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
School of Public Health Publications
School of Medicine Publications
 
Versions
Version Filter Type
Citation counts: Scopus Citation Count Cited 0 times in Scopus Article
Google Scholar Search Google Scholar
Created: Tue, 14 Feb 2017, 00:28:26 EST by System User on behalf of School of Medicine