Neonatal outcomes after prelabour rupture of membranes before 24 weeks' gestation

McLaughlin, Linda M. and Gardener, Glenn J. (2016) Neonatal outcomes after prelabour rupture of membranes before 24 weeks' gestation. Journal of Paediatrics and Child Health, 52 7: 722-727. doi:10.1111/jpc.13210


Author McLaughlin, Linda M.
Gardener, Glenn J.
Title Neonatal outcomes after prelabour rupture of membranes before 24 weeks' gestation
Journal name Journal of Paediatrics and Child Health   Check publisher's open access policy
ISSN 1034-4810
1440-1754
Publication date 2016-07-01
Year available 2016
Sub-type Article (original research)
DOI 10.1111/jpc.13210
Open Access Status Not yet assessed
Volume 52
Issue 7
Start page 722
End page 727
Total pages 6
Place of publication Chichester, West Sussex, United Kingdom
Publisher Wiley-Blackwell Publishing
Collection year 2017
Language eng
Formatted abstract
Aim: The aim of this study was to determine neonatal outcomes in pregnancies complicated by prelabour rupture of membranes (PROM) before 24 weeks' gestation.

Methods: We performed a retrospective review of medical records over a 5-year period (2007–2011) at Mater Health Services, South Brisbane, Australia. Data relating to the antenatal and perinatal course of pregnancies complicated by PROM before 24 weeks' gestation were collected. Data were also collected on neonatal diagnoses, management and outcomes for all liveborn infants resulting from these pregnancies.

Results: One hundred and six pregnancies were complicated by PROM before 24 weeks' gestation. Thirty-three (31%) of these pregnancies resulted in delivery at pre-viable gestations (<23 weeks). There were 36 (37%) infants who survived to hospital discharge. At discharge, 47% of infants had chronic lung disease, with 81% of this group requiring supplemental oxygen at home.

Conclusions: Almost one-third of pregnancies complicated by PROM before 24 weeks resulted in pre-viable preterm delivery. In pregnancies continuing to a viable gestation, there remained a significant risk of neonatal mortality and morbidity, primarily due to respiratory disease.
Keyword Fetal membrane
Infant
Newborn
Pregnancy outcome
Premature
Premature rupture
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

 
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Created: Thu, 18 Aug 2016, 21:35:58 EST by Julia McCabe on behalf of Learning and Research Services (UQ Library)