The effect of zinc supplementation on body composition and hormonal levels related to adiposity amongst children: a systematic review

Gunanti, Inong R., Al-Mamun, Abdullah, Schubert, Elizabeth C.R. (Lisa) and Long, Kurt Z. (2016) The effect of zinc supplementation on body composition and hormonal levels related to adiposity amongst children: a systematic review. Public Health Nutrition, . doi:10.1017/S1368980016001154


Author Gunanti, Inong R.
Al-Mamun, Abdullah
Schubert, Elizabeth C.R. (Lisa)
Long, Kurt Z.
Title The effect of zinc supplementation on body composition and hormonal levels related to adiposity amongst children: a systematic review
Journal name Public Health Nutrition   Check publisher's open access policy
ISSN 1368-9800
1475-2727
Publication date 2016-05-20
Year available 2016
Sub-type Article (original research)
DOI 10.1017/S1368980016001154
Open Access Status Not Open Access
Total pages 16
Place of publication Cambridge, United Kingdom
Publisher Cambridge University Press
Collection year 2017
Language eng
Formatted abstract
Objective: To provide a comprehensive synthesis of the effects of Zn supplementation on childhood body composition and adiposity-related hormone levels.

Design: Five electronic databases were searched for randomized controlled trials of Zn supplementation studies published before 28 February 2015. No statistical pooling of results was carried out due to diversity in study designs.

Setting: Community- or hospital-based, from fourteen developing and developed countries.

Subjects: Children and adolescents aged 0 to 10 years.

Results: Seven of the fourteen studies reported an overall or subgroup effect of Zn supplementation on at least one parameter of body composition, when determined by anthropometric measurements (increased mid upper-arm circumference, triceps skinfold, subscapular skinfold and mid upper-arm muscle area, and decreased BMI). Three out of the fourteen studies reported increased mean value of total body water estimated by bio-impedance analysis and increased fat-free mass estimated by dual energy X-ray absorptiometry and by total body water. Zn supplementation was associated with increased fat-free mass among stunted children. One study found supplementation decreased leptin and insulin concentrations.

Conclusions: Due to the use of anthropometry when determining body composition, a majority of the studies could not accurately address whether alterations in the fat and/or fat-free mass components of the body were responsible for the observed changes in body composition. The effect of Zn supplementation on body composition is not consistent but may modify fat-free mass among children with pre-existing growth failure.
Keyword Zinc supplementation
Body composition
Adiposity
Adiposity-related hormone
Children
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
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Created: Tue, 09 Aug 2016, 14:42:04 EST by Lisa Schubert on behalf of School of Public Health