Ethnic differences in cardiometabolic risk among adolescents across the waist-height ratio spectrum: National Health and Nutrition Examination Surveys (NHANES)

Dong, Bin, Arnold, Luke W., Peng, Yang and Wang, Zhiqiang (2016) Ethnic differences in cardiometabolic risk among adolescents across the waist-height ratio spectrum: National Health and Nutrition Examination Surveys (NHANES). International Journal of Cardiology, 222 622-628. doi:10.1016/j.ijcard.2016.07.169


Author Dong, Bin
Arnold, Luke W.
Peng, Yang
Wang, Zhiqiang
Title Ethnic differences in cardiometabolic risk among adolescents across the waist-height ratio spectrum: National Health and Nutrition Examination Surveys (NHANES)
Journal name International Journal of Cardiology   Check publisher's open access policy
ISSN 0167-5273
1874-1754
Publication date 2016-11-01
Year available 2016
Sub-type Article (original research)
DOI 10.1016/j.ijcard.2016.07.169
Open Access Status Not yet assessed
Volume 222
Start page 622
End page 628
Total pages 7
Place of publication Shannon, Clare Ireland
Publisher Elsevier Ireland
Collection year 2017
Language eng
Formatted abstract
Background: Although large waist–height ratio (WHtR) is associated with increased cardiometabolic risks, its ethnic difference in adolescents is unclear. This study aimed to investigate the ethnic differences in cardiometabolic risk across the WHtR spectrum among adolescents.

Methods:
Data for this cross-sectional study were obtained from National Health and Nutrition Examination Surveys (2001–2014), and a total of 7385 participants aged 12–17 years were involved. The associations between WHtR and cardiometabolic outcomes measures were assessed with fractional polynomial regression and logistic regression models.

Results:
The risk of all cardiometabolic risk factors increased with increasing WHtR. However, significant ethnic differences in risk of adverse cardiometabolic outcomes were observed across the WHtR spectrum. At a WHtR of 0.5, compared with non Hispanic (NH) whites, NH blacks revealed higher risks of elevated HbA1c, insulin resistance and hypertension, and lower risks of abnormal lipid profile, high glucose, elevated uric acid, and metabolic syndrome, with odds ratios (ORs) ranging from 1.36 (95% confidence interval: 1.17, 1.55) to 4.81 (2.94, 6.67) and 0.33 (0.23, 0.43) to 0.72 (0.53, 0.91), respectively. Additionally, significant differences in risks of abnormal lipid profile, elevated uric acid, abnormal glucose and insulin resistance were observed between Mexican Americans and NH whites as well.

Conclusions:
Significant ethnic disparities in cardiometabolic risk were observed in adolescents across the WHtR spectrum. Our findings pointed to opportunities to target particular cardiometabolic risk factors in specific ethnicities, and suggested the development of ethnicity-specific WHtR thresholds.
Keyword Waist–height ratio
Cardiovascular disease
Ethnic groups
Adolescent
Epidemiology
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ
Additional Notes http://www.internationaljournalofcardiology.com/article/S0167-5273(16)31564-9/fulltext

Document type: Journal Article
Sub-type: Article (original research)
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Created: Tue, 09 Aug 2016, 13:43:17 EST by Bin Dong on behalf of Medicine - Royal Brisbane and Women's Hospital