Environmentally-Induced changes in the brains of elderly rats

Cummins R.A., Walsh R.N., Budtz-Olsen O.E., Konstantinos T. and Horsfall C.R. (1973) Environmentally-Induced changes in the brains of elderly rats. Nature, 243 5409: 516-518. doi:10.1038/243516a0


Author Cummins R.A.
Walsh R.N.
Budtz-Olsen O.E.
Konstantinos T.
Horsfall C.R.
Title Environmentally-Induced changes in the brains of elderly rats
Journal name Nature   Check publisher's open access policy
ISSN 0028-0836
Publication date 1973
Sub-type Article (original research)
DOI 10.1038/243516a0
Volume 243
Issue 5409
Start page 516
End page 518
Total pages 3
Subject 1000 General
Abstract ANIMALS that have been exposed to environmental stimulation develop marked differences in brain structure and biochemistry when compared with animals that have not been exposed in this way1-4. Factors influencing the magnitude of these changes are the duration of rearing and the age of the animals when the environmental separation takes place. Most studies have focused on young animals because the brain is thought to be more plastic at this stage. As a result, temporal analyses of the induced changes have usually been limited to fairly short periods of environmental exposure early in the animal's life. Rosenzweig et al.3 have suggested that, in rats differentially reared from weaning, the induced differences in brain weight reach a maximum during the first 30 d of separation, after which they decrease. But the evidence for this biphasic response has been based on relatively short periods of differential rearing (15-160 d).
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import
 
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