Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)

Sartelli, Massimo, Weber, Dieter G., Ruppe, Etienne, Bassetti, Matteo, Wright, Brian J., Ansaloni, Luca, Catena, Fausto, Coccolini, Federico, Abu-Zidan, Fikri M., Coimbra, Raul, Moore, Ernest E., Moore, Frederick A., Maier, Ronald V., De Waele, Jan J., Kirkpatrick, Andrew W., Griffiths, Ewen A., Eckmann, Christian, Brink, Adrian J., Mazuski, John E., May, Addison K., Sawyer, Rob G., Mertz, Dominik, Montravers, Philippe, Kumar, Anand, Roberts, Jason A., Vincent, Jean-Louis, Watkins, Richard R., Lowman, Warren, Spellberg, Brad, Abbott, Iain J., Adesunkanmi, Abdulrashid Kayode, Al-Dahir, Sara, Al-Hasan, Majdi N., Agresta, Ferdinando, Althani, Asma A., Ansari, Shamshul, Ansumana, Rashid, Augustin, Goran, Bala, Miklosh, Balogh, Zsolt J., Baraket, Oussama, Bhangu, Aneel, Beltran, Marcelo A., Bernhard, Michael, Biffl, Walter L., Boermeester, Marja A., Brecher, Stephen M., Cherry-Bukowiec, Jill R., Buyne, Otmar R., Cainzos, Miguel A., Cairns, Kelly A., Camacho-Ortiz, Adrian, Chandy, Sujith J., Jusoh, Asri Che, Chichom-Mefire, Alain, Colijn, Caroline, Corcione, Francesco, Cui, Yunfeng, Curcio, Daniel, Delibegovic, Samir, Demetrashvili, Zaza, De Simone, Belinda, Dhingra, Sameer, Diaz, Jose J., Di Carlo, Isidoro, Dillip, Angel, Di Saverio, Salomone, Doyle, Michael P., Dorj, Gereltuya, Dogjani, Agron, Dupont, Herve, Eachempati, Soumitra R., Enani, Mushira Abdulaziz, Egiev, Valery N., Elmangory, Mutasim M., Ferrada, Paula, Fitchett, Joseph R., Fraga, Gustavo P., Guessennd, Nathalie, Giamarellou, Helen, Ghnnam, Wagih, Gkiokas, George, Goldberg, Staphanie R., Gomes, Carlos Augusto, Gomi, Harumi, Guzman-Blanco, Manuel, Haque, Mainul, Hansen, Sonja, Hecker, Andreas, Heizmann, Wolfgang R., Herzog, Torsten, Hodonou, Adrien Montcho, Hong, Suk-Kyung, Kafka-Ritsch, Reinhold, Kaplan, Lewis J., Kapoor, Garima, Karamarkovic, Aleksandar, Kees, Martin G., Kenig, Jakub, Kiguba, Ronald, Kim, Peter K., Kluger, Yoram, Khokha, Vladimir, Koike, Kaoru, Kok, Kenneth Y. Y., Kong, Victory, Knox, Matthew C., Inaba, Kenji, Isik, Arda, Iskandar, Katia, Ivatury, Rao R., Labbate, Maurizio, Labricciosa, Francesco M., Laterre, Pierre-Francois, Latifi, Rifat, Lee, Jae Gil, Lee, Young Ran, Leone, Marc, Leppaniemi, Ari, Li, Yousheng, Liang, Stephen Y., Loho, Tonny, Maegele, Marc, Malama, Sydney, Marei, Hany E., Martin-Loeches, Ignacio, Marwah, Sanjay, Massele, Amos, McFarlane, Michael, Melo, Renato Bessa, Negoi, Ionut, Nicolau, David P., Nord, Carl Erik, Ofori-Asenso, Richard, Omari, AbdelKarim H., Ordonez, Carlos A., Ouadii, Mouaqit, Pereira Junior, Gerson Alves, Piazza, Diego, Pupelis, Guntars, Rawson, Timothy Miles, Rems, Miran, Rizoli, Sandro, Rocha, Claudio, Sakakhushev, Boris, Sanchez-Garcia, Miguel, Sato, Norio, Lohse, Helmut A. Segovia, Sganga, Gabriele, Siribumrungwong, Boonying, Shelat, Vishal G., Soreide, Kjetil, Soto, Rodolfo, Talving, Peep, Tilsed, Jonathan V., Timsit, Jean-Francois, Trueba, Gabriel, Trung, Ngo Tat, Ulrych, Jan, van Goor, Harry, Vereczkei, Andras, Vohra, Ravinder S., Wani, Imtiaz, Uhl, Waldemar, Xiao, Yonghong, Yuan, Kuo-Ching, Zachariah, Sanoop K., Zahar, Jean-Ralph, Zakrison, Tanya L., Corcione, Antonio, Melotti, Rita M., Viscoli, Claudio and Viale, Perluigi (2016) Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA). World Journal of Emergency Surgery, 11 . doi:10.1186/s13017-016-0089-y


Author Sartelli, Massimo
Weber, Dieter G.
Ruppe, Etienne
Bassetti, Matteo
Wright, Brian J.
Ansaloni, Luca
Catena, Fausto
Coccolini, Federico
Abu-Zidan, Fikri M.
Coimbra, Raul
Moore, Ernest E.
Moore, Frederick A.
Maier, Ronald V.
De Waele, Jan J.
Kirkpatrick, Andrew W.
Griffiths, Ewen A.
Eckmann, Christian
Brink, Adrian J.
Mazuski, John E.
May, Addison K.
Sawyer, Rob G.
Mertz, Dominik
Montravers, Philippe
Kumar, Anand
Roberts, Jason A.
Vincent, Jean-Louis
Watkins, Richard R.
Lowman, Warren
Spellberg, Brad
Abbott, Iain J.
Adesunkanmi, Abdulrashid Kayode
Al-Dahir, Sara
Al-Hasan, Majdi N.
Agresta, Ferdinando
Althani, Asma A.
Ansari, Shamshul
Ansumana, Rashid
Augustin, Goran
Bala, Miklosh
Balogh, Zsolt J.
Baraket, Oussama
Bhangu, Aneel
Beltran, Marcelo A.
Bernhard, Michael
Biffl, Walter L.
Boermeester, Marja A.
Brecher, Stephen M.
Cherry-Bukowiec, Jill R.
Buyne, Otmar R.
Cainzos, Miguel A.
Cairns, Kelly A.
Camacho-Ortiz, Adrian
Chandy, Sujith J.
Jusoh, Asri Che
Chichom-Mefire, Alain
Colijn, Caroline
Corcione, Francesco
Cui, Yunfeng
Curcio, Daniel
Delibegovic, Samir
Demetrashvili, Zaza
De Simone, Belinda
Dhingra, Sameer
Diaz, Jose J.
Di Carlo, Isidoro
Dillip, Angel
Di Saverio, Salomone
Doyle, Michael P.
Dorj, Gereltuya
Dogjani, Agron
Dupont, Herve
Eachempati, Soumitra R.
Enani, Mushira Abdulaziz
Egiev, Valery N.
Elmangory, Mutasim M.
Ferrada, Paula
Fitchett, Joseph R.
Fraga, Gustavo P.
Guessennd, Nathalie
Giamarellou, Helen
Ghnnam, Wagih
Gkiokas, George
Goldberg, Staphanie R.
Gomes, Carlos Augusto
Gomi, Harumi
Guzman-Blanco, Manuel
Haque, Mainul
Hansen, Sonja
Hecker, Andreas
Heizmann, Wolfgang R.
Herzog, Torsten
Hodonou, Adrien Montcho
Hong, Suk-Kyung
Kafka-Ritsch, Reinhold
Kaplan, Lewis J.
Kapoor, Garima
Karamarkovic, Aleksandar
Kees, Martin G.
Kenig, Jakub
Kiguba, Ronald
Kim, Peter K.
Kluger, Yoram
Khokha, Vladimir
Koike, Kaoru
Kok, Kenneth Y. Y.
Kong, Victory
Knox, Matthew C.
Inaba, Kenji
Isik, Arda
Iskandar, Katia
Ivatury, Rao R.
Labbate, Maurizio
Labricciosa, Francesco M.
Laterre, Pierre-Francois
Latifi, Rifat
Lee, Jae Gil
Lee, Young Ran
Leone, Marc
Leppaniemi, Ari
Li, Yousheng
Liang, Stephen Y.
Loho, Tonny
Maegele, Marc
Malama, Sydney
Marei, Hany E.
Martin-Loeches, Ignacio
Marwah, Sanjay
Massele, Amos
McFarlane, Michael
Melo, Renato Bessa
Negoi, Ionut
Nicolau, David P.
Nord, Carl Erik
Ofori-Asenso, Richard
Omari, AbdelKarim H.
Ordonez, Carlos A.
Ouadii, Mouaqit
Pereira Junior, Gerson Alves
Piazza, Diego
Pupelis, Guntars
Rawson, Timothy Miles
Rems, Miran
Rizoli, Sandro
Rocha, Claudio
Sakakhushev, Boris
Sanchez-Garcia, Miguel
Sato, Norio
Lohse, Helmut A. Segovia
Sganga, Gabriele
Siribumrungwong, Boonying
Shelat, Vishal G.
Soreide, Kjetil
Soto, Rodolfo
Talving, Peep
Tilsed, Jonathan V.
Timsit, Jean-Francois
Trueba, Gabriel
Trung, Ngo Tat
Ulrych, Jan
van Goor, Harry
Vereczkei, Andras
Vohra, Ravinder S.
Wani, Imtiaz
Uhl, Waldemar
Xiao, Yonghong
Yuan, Kuo-Ching
Zachariah, Sanoop K.
Zahar, Jean-Ralph
Zakrison, Tanya L.
Corcione, Antonio
Melotti, Rita M.
Viscoli, Claudio
Viale, Perluigi
Title Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)
Journal name World Journal of Emergency Surgery   Check publisher's open access policy
ISSN 1749-7922
Publication date 2016-07-15
Year available 2016
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1186/s13017-016-0089-y
Open Access Status DOI
Volume 11
Total pages 32
Place of publication London, United Kingdom
Publisher BioMed Central
Collection year 2017
Language eng
Formatted abstract
Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients. The cornerstones in the management of complicated IAIs are timely effective source control with appropriate antimicrobial therapy. Empiric antimicrobial therapy is important in the management of intra-abdominal infections and must be broad enough to cover all likely organisms because inappropriate initial antimicrobial therapy is associated with poor patient outcomes and the development of bacterial resistance. The overuse of antimicrobials is widely accepted as a major driver of some emerging infections (such as C. difficile), the selection of resistant pathogens in individual patients, and for the continued development of antimicrobial resistance globally. The growing emergence of multi-drug resistant organisms and the limited development of new agents available to counteract them have caused an impending crisis with alarming implications, especially with regards to Gram-negative bacteria. An international task force from 79 different countries has joined this project by sharing a document on the rational use of antimicrobials for patients with IAIs. The project has been termed AGORA (Antimicrobials: A Global Alliance for Optimizing their Rational Use in Intra-Abdominal Infections). The authors hope that AGORA, involving many of the world's leading experts, can actively raise awareness in health workers and can improve prescribing behavior in treating IAIs.
Keyword Intra-abdominal infections (IAI)
Morbidity
High-risk patients
Antimicrobial therapy
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
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