Selection on optimal haploid value increases genetic gain and preserves more genetic diversity relative to genomic selection

Daetwyler, Hans D., Hayden, Matthew J., Spangenberg, German C. and Hayes, Ben J. (2015) Selection on optimal haploid value increases genetic gain and preserves more genetic diversity relative to genomic selection. Genetics, 200 4: 1341-1348. doi:10.1534/genetics.115.178038


Author Daetwyler, Hans D.
Hayden, Matthew J.
Spangenberg, German C.
Hayes, Ben J.
Title Selection on optimal haploid value increases genetic gain and preserves more genetic diversity relative to genomic selection
Journal name Genetics   Check publisher's open access policy
ISSN 1943-2631
Publication date 2015-08-01
Year available 2015
Sub-type Article (original research)
DOI 10.1534/genetics.115.178038
Open Access Status Not Open Access
Volume 200
Issue 4
Start page 1341
End page 1348
Total pages 8
Place of publication Bethesda, United States
Publisher Genetics Society of America
Language eng
Formatted abstract
Doubled haploids are routinely created and phenotypically selected in plant breeding programs to accelerate the breeding cycle. Genomic selection, which makes use of both phenotypes and genotypes, has been shown to further improve genetic gain through prediction of performance before or without phenotypic characterization of novel germplasm. Additional opportunities exist to combine genomic prediction methods with the creation of doubled haploids. Here we propose an extension to genomic selection, optimal haploid value (OHV) selection, which predicts the best doubled haploid that can be produced from a segregating plant. This method focuses selection on the haplotype and optimizes the breeding program toward its end goal of generating an elite fixed line. We rigorously tested OHV selection breeding programs, using computer simulation, and show that it results in up to 0.6 standard deviations more genetic gain than genomic selection. At the same time, OHV selection preserved a substantially greater amount of genetic diversity in the population than genomic selection, which is important to achieve long-term genetic gain in breeding populations.
Keyword Doubled haploid
Genetic diversity
Genetic gain
Genomic selection
GenPred
Haplotype
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Queensland Alliance for Agriculture and Food Innovation
 
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