Sampling strategies for whole genome association studies in aquaculture and outcrossing plant species

Hayes, B. J., MacLeod, I. M. and Baranski, M. (2009) Sampling strategies for whole genome association studies in aquaculture and outcrossing plant species. Genetics Research, 91 6: 367-371. doi:10.1017/S0016672309990310


Author Hayes, B. J.
MacLeod, I. M.
Baranski, M.
Title Sampling strategies for whole genome association studies in aquaculture and outcrossing plant species
Journal name Genetics Research   Check publisher's open access policy
ISSN 0016-6723
Publication date 2009-12
Sub-type Article (original research)
DOI 10.1017/S0016672309990310
Open Access Status Not yet assessed
Volume 91
Issue 6
Start page 367
End page 371
Total pages 5
Place of publication Cambridge, United Kingdom
Publisher Cambridge University Press
Language eng
Abstract A number of farmed species are characterized by breeding populations of large full-sib families, including aquaculture species and outcrossing plant species. Whole genome association studies in such species must account for stratification arising from the full-sib family structure to avoid high rates of false discovery. Here, we demonstrate the value of selective genotyping strategies which balance the contribution of families across high and low phenotypes to greatly reduce rates of false discovery with a minimal effect on power.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Queensland Alliance for Agriculture and Food Innovation
 
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