Detection of chromosome segments of zebu and taurine origin and their effect on beef production and growth

Bolormaa, S., Hayes, B. J., Hawken, R. J., Zhang, Y., Reverter, A. and Goddard, M. E. (2014) Detection of chromosome segments of zebu and taurine origin and their effect on beef production and growth. Journal of Animal Science, 89 7: 2050-2060. doi:10.2527/jas.2010-3363

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Author Bolormaa, S.
Hayes, B. J.
Hawken, R. J.
Zhang, Y.
Reverter, A.
Goddard, M. E.
Title Detection of chromosome segments of zebu and taurine origin and their effect on beef production and growth
Journal name Journal of Animal Science   Check publisher's open access policy
ISSN 0021-8812
1525-3163
Publication date 2014-12-04
Sub-type Article (original research)
DOI 10.2527/jas.2010-3363
Open Access Status File (Publisher version)
Volume 89
Issue 7
Start page 2050
End page 2060
Total pages 11
Place of publication Champaign, IL, United States
Publisher American Society of Animal Science
Language eng
Formatted abstract
Cattle in breeds formed by recent crossing of Bos taurus (Bt) and Bos indicus (Bi) subspecies should contain chromosomes that are a composite of Bt and Bt segments. Using data from a 50K SNP chip, we were able to identify whether a chromosome segment of 11 SNP in a composite animal descended from a Bt or a Bi ancestor. When the method was tested in purebred Bt or Brahman cattle, about 94% of segments were assigned correctly. About 10% of the genome in Australian Brahman cattle appears to be of Bt origin, as might be expected from their history. We then examined the effect of the origin of each chromosome segment on BW in a population of 515 Bt × Bi composite cattle and found 67 chromosome segments with a significant (P < 0.01) effect. We confirmed these effects by examining these 67 segments in a population of Brahman cattle and in a population of mixed breeds including composite breeds such as Santa Gertrudis and Brahman cattle. About 66% of the 67 segments had an effect in the same direction in the confirmation analyses as in the discovery population. However, the effect on BW and other traits of chromosome segment origin is small, indicating that we had low power to detect these effects with the number of animals available. Consequently, when chromosome segment origin was used in genomic selection to predict BW, the accuracy was low (0.08). Chromosome segments that had a positive effect on BW tend to be at greater frequency in composite breeds than chromosome segments with a negative effect on BW.
Keyword Chromosome segment
Genome-wide association study
Haplotype
Single nucleotide polymorphism
Taurine
Zebu
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Queensland Alliance for Agriculture and Food Innovation
 
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