Passive transfer of immunity with serum in mice infected with Nematospiroides dubius: Influence of quality and quantity of immune serum

Dobson C. (1982) Passive transfer of immunity with serum in mice infected with Nematospiroides dubius: Influence of quality and quantity of immune serum. International Journal for Parasitology, 12 2-3: 207-213. doi:10.1016/0020-7519(82)90018-2


Author Dobson C.
Title Passive transfer of immunity with serum in mice infected with Nematospiroides dubius: Influence of quality and quantity of immune serum
Journal name International Journal for Parasitology   Check publisher's open access policy
ISSN 0020-7519
Publication date 1982
Sub-type Article (original research)
DOI 10.1016/0020-7519(82)90018-2
Volume 12
Issue 2-3
Start page 207
End page 213
Total pages 7
Subject 2405 Parasitology
2725 Infectious Diseases
Abstract Dobson C. 1982. Passive transfer of immunity with serum in mice infected with Nematospiroides dubius: influence of quality and quantity of immune serum. International Journal for Parasitology 12: 207-213. The passive transfer of protective immunity to mice with immune serum against Nematospiroides dubius infection was directly proportional to the number of infections experienced by the serum donor mice and the antibody titre and quantity of serum transferred to each recipient. These effects were seen as decreased parasite survival, stunting of growth and reduced parasite fecundity. Male worms were more susceptible to the effects of immune serum than female worms. Immune serum from female donors was more efficacious than that from males in protecting mice against infection. Passively immunized male mice harboured more worms than females given the same serum. Antibody appeared to debilitate the parasite both directly, by influencing its biology and indirectly by reducing its survival.
Keyword antibodies
immunity
mice
Nematospiroides dubius
passive serum transfer
sex
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import
 
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Created: Tue, 26 Jul 2016, 04:44:44 EST by System User