A quantitative evaluation of the aetiological role of betel quid in oral carcinogenesis

Thomas S. and Wilson A. (1993) A quantitative evaluation of the aetiological role of betel quid in oral carcinogenesis. European Journal of Cancer. Part B: Oral Oncology, 29 4: 265-271. doi:10.1016/0964-1955(93)90046-H


Author Thomas S.
Wilson A.
Title A quantitative evaluation of the aetiological role of betel quid in oral carcinogenesis
Journal name European Journal of Cancer. Part B: Oral Oncology   Check publisher's open access policy
ISSN 0964-1955
Publication date 1993
Sub-type Article (original research)
DOI 10.1016/0964-1955(93)90046-H
Volume 29
Issue 4
Start page 265
End page 271
Total pages 7
Subject 1306 Cancer Research
2730 Oncology
Abstract Computer aided search and review of bibliographies of published papers and monographs revealed 17 case control studies of oral cancer and betel quid chewing from 1933 to 1990. Studies were assessed and site specific risk of oral cancer associated with chewing betel quid with and without tobacco in the quid among smokers and non-smokers was computed. Tobacco smoking and chewing betal quid containing tobacco arose as important risk factors for oral cancer, betel quid without tobacco significantly increased risk in only one study. Heterogeneity in estimates of risk among studies was reduced by restricting analysis to those with more exact definition of exposure and site of the cancer. Variation in risk among studies reflects bias in selection and inadequate definition of exposure and tumour site and an inability to control effectively for confounding. Further studies, addressing these issues are advised, to clarify the role of betel quid without tobacco as a carcinogen, alone and in combination with tobacco smoke.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import
 
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Created: Tue, 26 Jul 2016, 04:30:17 EST by System User