Neuropeptides in physiologically identified mammalian sensory neurones

Leah J.D., Cameron A.A. and Snow P.J. (1985) Neuropeptides in physiologically identified mammalian sensory neurones. Neuroscience Letters, 56 3: 257-263. doi:10.1016/0304-3940(85)90252-6


Author Leah J.D.
Cameron A.A.
Snow P.J.
Title Neuropeptides in physiologically identified mammalian sensory neurones
Journal name Neuroscience Letters   Check publisher's open access policy
ISSN 0304-3940
Publication date 1985-05-23
Sub-type Article (original research)
DOI 10.1016/0304-3940(85)90252-6
Volume 56
Issue 3
Start page 257
End page 263
Total pages 7
Subject 2800 Neuroscience
Abstract In cats, intracellular dye injection of single sensory neurones of known fibre type and sensory modality has been combined with peptide immunohistochemistry. There was no clear relationship between the sensory function of a neurone and the presence of the neuropeptides substance P, somatostatin, cholecystokinin and vasoactive intestinal polypeptide, in its cytoplasm. In particular, substance P was not detected in many nociceptive sensory neurons even though it could be demonstrated with the same technique in many sensory neurones which did not have cutaneous receptive fields. These results mean that the role, if any, of these neuropeptides in the transmission of pain, must be regarded as complex.
Keyword immunocytochemistry
neurotransmission
nociception
primary afferents
spinal cord
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import
 
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Created: Tue, 26 Jul 2016, 04:05:38 EST by System User