A door-to-door survey to estimate the prevalence of Parkinsonism in Pakistan

Khan, Suliman, Nabi, Ghulam, Naeem, Muhammad, Ali, Liaqat, Silburn, Peter A. and Mellick, George D. (2016) A door-to-door survey to estimate the prevalence of Parkinsonism in Pakistan. Neuropsychiatric Disease and Treatment, 12 1499-1506. doi:10.2147/NDT.S86329


Author Khan, Suliman
Nabi, Ghulam
Naeem, Muhammad
Ali, Liaqat
Silburn, Peter A.
Mellick, George D.
Title A door-to-door survey to estimate the prevalence of Parkinsonism in Pakistan
Journal name Neuropsychiatric Disease and Treatment   Check publisher's open access policy
ISSN 1178-2021
1176-6328
Publication date 2016-06-21
Year available 2016
Sub-type Article (original research)
DOI 10.2147/NDT.S86329
Open Access Status DOI
Volume 12
Start page 1499
End page 1506
Total pages 8
Place of publication Macclesfield, United Kingdom
Publisher Dove Medical Press
Collection year 2017
Language eng
Formatted abstract
Introduction: Parkinson’s disease (PD) occurs in all races and cultures, and population-related differences in frequency may provide etiological clues. The present study was designed to explore the prevalence of PD and Parkinsonism in Pakistan, the world’s sixth most populous country, for which no published prevalence data are available.

Methods: We conducted a three-phase door-to-door survey in two districts of the Khyber Pakhtunkhwa province of Pakistan, to assess the prevalence of PD and Parkinsonism in a sample of 4,000 individuals aged 50 years and above.

Results: We identified 14 cases of Parkinsonism, eleven with a diagnosis of idiopathic PD. The overall prevalence estimates were 1.7/100 (95% confidence interval [CI]: 0.9−2.46) for Parkinsonism and 1.28/100 (95% CI: 0.6−1.94) for PD in persons aged 65 years and above. The age-standardized prevalence of PD (aged 65 years and above), normalized to the USA population in 2000, was 1.33/100, which is similar to that observed in other human populations. Of the total 14 cases, five were newly diagnosed and four had a family history of PD.

Conclusion: The estimated prevalence rates in Pakistan are similar to those observed in other human populations. The frequency of familial Parkinsonism is also equivalent to previous estimates.
Keyword Door-to-door survey
Parkinsonism
Parkinson’s disease
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: UQ Centre for Clinical Research Publications
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