Canopy venom: proteomic comparison among new world arboreal pit-viper venoms

Debono, Jordan, Cochran, Chip, Kuruppu, Sanjaya, Nouwens, Amanda, Rajapakse, Niwanthi W., Kawasaki, Minami, Wood, Kelly, Dobson, James, Baumann, Kate, Jouiaei, Mahdokht, Jackson, Timothy N. W., Koludarov, Ivan, Low, Dolyce, Ali, Syed A., Smith, A. Ian, Barnes, Andrew and Fry, Bryan G. (2016) Canopy venom: proteomic comparison among new world arboreal pit-viper venoms. Toxins, 8 7: 210.1-210.19. doi:10.3390/toxins8070210

Author Debono, Jordan
Cochran, Chip
Kuruppu, Sanjaya
Nouwens, Amanda
Rajapakse, Niwanthi W.
Kawasaki, Minami
Wood, Kelly
Dobson, James
Baumann, Kate
Jouiaei, Mahdokht
Jackson, Timothy N. W.
Koludarov, Ivan
Low, Dolyce
Ali, Syed A.
Smith, A. Ian
Barnes, Andrew
Fry, Bryan G.
Title Canopy venom: proteomic comparison among new world arboreal pit-viper venoms
Journal name Toxins   Check publisher's open access policy
ISSN 2072-6651
Publication date 2016-07-08
Sub-type Article (original research)
DOI 10.3390/toxins8070210
Open Access Status DOI
Volume 8
Issue 7
Start page 210.1
End page 210.19
Total pages 19
Place of publication Basel, Switzerland
Publisher M D P I AG
Collection year 2017
Language eng
Formatted abstract
Central and South American pitvipers, belonging to the genera Bothrops and Bothriechis, have independently evolved arboreal tendencies. Little is known regarding the composition and activity of their venoms. In order to close this knowledge gap, venom proteomics and toxin activity of species of Bothriechis, and Bothrops (including Bothriopsis) were investigated through established analytical methods. A combination of proteomics and bioactivity techniques was used to demonstrate a similar diversification of venom composition between large and small species within Bothriechis and Bothriopsis. Increasing our understanding of the evolution of complex venom cocktails may facilitate future biodiscoveries.
Keyword Enzyme
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

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Created: Fri, 15 Jul 2016, 11:17:04 EST by Mrs Louise Nimwegen on behalf of School of Chemistry & Molecular Biosciences