Possible metformin-induced otorrhoea: a rare case

Maarup, Norlela, Palaian, Subish, Ibrahim, Mohamed Izham M, Khanal, Saval and Alshakka, Mohamed (2011) Possible metformin-induced otorrhoea: a rare case. Journal of Pharmacy Practice and Research, 41 1: 49-50. doi:10.1002/j.2055-2335.2011.tb00067.x

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Author Maarup, Norlela
Palaian, Subish
Ibrahim, Mohamed Izham M
Khanal, Saval
Alshakka, Mohamed
Title Possible metformin-induced otorrhoea: a rare case
Journal name Journal of Pharmacy Practice and Research   Check publisher's open access policy
ISSN 2055-2335
1445-937X
Publication date 2011-03
Sub-type Letter to editor, brief commentary or brief communication
DOI 10.1002/j.2055-2335.2011.tb00067.x
Open Access Status Not Open Access
Volume 41
Issue 1
Start page 49
End page 50
Total pages 2
Place of publication Chichester, West Sussex United Kingdom
Publisher Wiley-Blackwell Publishing
Language eng
Formatted abstract
Background

Ear problems attributed to metformin use are not documented in the literature.

Aim

To report a possible case of otorrhoea from metformin therapy.

Clinical details

A 50-year-old male developed an ear discharge during metformin therapy.

Outcomes

His ear discharge reappeared when metformin was reintroduced and disappeared when it was discontinued, suggesting a possible association between metformin and otorrhoea. The causality assessment revealed a “probable” (Naranjo algorithm score 8) association and the severity was ‘moderate’ (Level 3).

Conclusion

First case of possible otorrhoea from metformin therapy to be reported in the literature.
Keyword Pharmacovigilance
Clinical pharmacy
Metformin induced otorrhoea
Q-Index Code CX
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Letter to editor, brief commentary or brief communication
Collection: School of Pharmacy Publications
 
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Created: Wed, 13 Jul 2016, 13:36:11 EST by Saval Khanal on behalf of School of Pharmacy