Prospective associations between depression and obesity for adolescent males and females- a systematic review and meta-analysis of longitudinal studies

Mannan, Munim, Mamun, Abdullah, Doi, Suhail and Clavarino, Alexandra (2016) Prospective associations between depression and obesity for adolescent males and females- a systematic review and meta-analysis of longitudinal studies. Plos One, 11 6: . doi:10.1371/journal.pone.0157240


Author Mannan, Munim
Mamun, Abdullah
Doi, Suhail
Clavarino, Alexandra
Title Prospective associations between depression and obesity for adolescent males and females- a systematic review and meta-analysis of longitudinal studies
Journal name Plos One   Check publisher's open access policy
ISSN 1932-6203
Publication date 2016-06-10
Year available 2016
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1371/journal.pone.0157240
Open Access Status DOI
Volume 11
Issue 6
Total pages 18
Place of publication San Francisco, CA, United States
Publisher Public Library of Science
Collection year 2017
Language eng
Abstract Adolescent obesity and depression are increasingly prevalent and are currently recognised as major public health concerns worldwide. The aim of this study is to evaluate the bi-directional associations between obesity and depression in adolescents using longitudinal studies. A systematic literature search was conducted using Pubmed (including Medline), PsycINFO, Embase, CINAHL, BIOSIS Preview and the Cochrane Library databases. According to the inclusion criteria, 13 studies were found where seven studies evaluated depression leading to obesity and six other studies examined obesity leading to depression. Using a bias-adjusted quality effects model for the meta-analysis, we found that adolescents who were depressed had a 70% (RR 1.70, 95% CI: 1.40, 2.07) increased risk of being obese, conversely obese adolescents had an increased risk of 40% (RR 1.40, 95% CI: 1.16, 1.70) of being depressed. The risk difference (RD) of early adolescent depression leading to obesity is 3% higher risk than it is for obesity leading to depression. In sensitivity analysis, the association between depression leading to obesity was greater than that of obesity leading to depression for females in early adulthood compared with females in late adolescence. Overall, the findings of this study suggest a bi-directional association between depression and obesity that was stronger for female adolescents. However, this finding also underscores the importance of early detection and treatment strategies to inhibit the development of reciprocal disorders.
Keyword Obesity
Depression
Adolescent males
Adolescent females
Risk difference (RD)
Bi-directional association
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: HERDC Pre-Audit
School of Public Health Publications
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