A prospective comparison between magnetic resonance imaging, meta-iodobenzylguanidine scintigraphy and marrow histology/cytology in neuroblastoma

Corbett, R, Olliff, J, Fairley, N, Moyes, J, Husband, J, Pinkerton, R, Carter, R, Treleaven, J, McElwain, T and Meller, S (1991) A prospective comparison between magnetic resonance imaging, meta-iodobenzylguanidine scintigraphy and marrow histology/cytology in neuroblastoma. European Journal of Cancer and Clinical Oncology, 27 12: 1560-1564. doi:10.1016/0277-5379(91)90415-A


Author Corbett, R
Olliff, J
Fairley, N
Moyes, J
Husband, J
Pinkerton, R
Carter, R
Treleaven, J
McElwain, T
Meller, S
Title A prospective comparison between magnetic resonance imaging, meta-iodobenzylguanidine scintigraphy and marrow histology/cytology in neuroblastoma
Journal name European Journal of Cancer and Clinical Oncology   Check publisher's open access policy
ISSN 0277-5379
Publication date 1991
Sub-type Article (original research)
DOI 10.1016/0277-5379(91)90415-A
Volume 27
Issue 12
Start page 1560
End page 1564
Total pages 5
Language eng
Subject 2730 Oncology
1306 Cancer Research
Abstract A prospective comparison between magnetic resonance imaging (MRI), 123I meta-iodobenzylguanidine (mIBG) scintigraphy and posterior iliac crest marrow aspiration and trephine biopsy in 30 assessments (19 patients) showed concordance between the three techniques in 16 assessments (53.3%). In 10 (33.3%), MRI and mIBG revealed abnormalities not detected by marrow biopsy. MRI was the only technique to demonstrate marrow abnormality in four assessments (13.3%). In addition, MRI revealed more sites of abnormality in 16 parallel assessments. We conclude that MRI shows promise as a non-invasive means of detecting bone marrow infiltration by neuroblastoma, but that further evaluation of the specificity of MRI in this setting is indicated.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
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Citation counts: TR Web of Science Citation Count  Cited 27 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 28 times in Scopus Article | Citations
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