A selective review of possible neurological etiologies of schizophrenia

Berquier A. and Ashton R. (1991) A selective review of possible neurological etiologies of schizophrenia. Clinical Psychology Review, 11 5: 645-661. doi:10.1016/0272-7358(91)90008-I


Author Berquier A.
Ashton R.
Title A selective review of possible neurological etiologies of schizophrenia
Journal name Clinical Psychology Review   Check publisher's open access policy
ISSN 0272-7358
Publication date 1991
Sub-type Article (original research)
DOI 10.1016/0272-7358(91)90008-I
Volume 11
Issue 5
Start page 645
End page 661
Total pages 17
Subject 2738 Psychiatry and Mental health
3203 Clinical Psychology
Abstract Attempts to research the biological correlates and etiology of schizophrenia have suffered from a lack of clear diagnostic differentiation. Proposed classifications of acute/chronic, paranoid/nonparanoid, and negative symptom/positive symptom lack sufficient discrimination between subgroups. Recent research on biochemical neurotransmission, particularly in the activity of dopamine and neuropeptides, in conjunction with neuropathological research into structural abnormalities, has led to a 2-syndrome hypothesis. The viral theory has recently been rejuvenated in light of the discovery of genetically transmitted retroviruses and confirmation of the season of birth effect in the Northern Hemisphere. Unfortunately, problems of neuroleptic drugs effects, the role of secondary symptoms, significant overlap between groups, and inconsistent results continue to confound comprehensive interpretation.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import
 
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Created: Tue, 05 Jul 2016, 03:56:52 EST by System User