A comparison of maternal serum levels of alpha-fetoprotein in normal and pre-eclamptic pregnancies

Khoo S.K., Chang A. and Mackay E.V. (1978) A comparison of maternal serum levels of alpha-fetoprotein in normal and pre-eclamptic pregnancies. British Journal of Obstetrics and Gynaecology, 85 12: 914-920. doi:10.1111/j.1471-0528.1978.tb15853.x


Author Khoo S.K.
Chang A.
Mackay E.V.
Title A comparison of maternal serum levels of alpha-fetoprotein in normal and pre-eclamptic pregnancies
Journal name British Journal of Obstetrics and Gynaecology   Check publisher's open access policy
ISSN 0306-5456
Publication date 1978
Sub-type Article (original research)
DOI 10.1111/j.1471-0528.1978.tb15853.x
Volume 85
Issue 12
Start page 914
End page 920
Total pages 7
Subject 2729 Obstetrics and Gynaecology
Abstract Alpha-fetoprotein (AFP) concentrations were measured by radioimmunoassay in serum from women with normal and pre-eclamptic pregnancies. An analysis of the results obtained in normal pregnancy was made using arithmetic and semi-logarithmic scales, and a statistical conversion of the AFP values in relation to gestational age was introduced to allow an easier interpretation of results. In pre-eclampsia, significantly lower mean AFP values were obtained, with the majority of individual values being lower than the mean for normal pregnancy. These low levels were not associated with fetal death, but appeared to be related to the severity of disease. The significance of these findings remains to be evaluated.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import
 
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Created: Tue, 05 Jul 2016, 01:22:33 EST by System User