In vivo localized1 H spectroscopy of the rat eye at 7 T: preliminary studies

Crozier S. and Doddrell D.M. (1995) In vivo localized1 H spectroscopy of the rat eye at 7 T: preliminary studies. MAGMA Magnetic Resonance Materials in Physics, Biology, and Medicine, 3 3-4: 137-141. doi:10.1007/BF01771698


Author Crozier S.
Doddrell D.M.
Title In vivo localized1 H spectroscopy of the rat eye at 7 T: preliminary studies
Journal name MAGMA Magnetic Resonance Materials in Physics, Biology, and Medicine   Check publisher's open access policy
ISSN 0968-5243
Publication date 1995
Sub-type Article (original research)
DOI 10.1007/BF01771698
Volume 3
Issue 3-4
Start page 137
End page 141
Total pages 5
Publisher Kluwer Academic Publishers
Subject 1311 Genetics
1304 Biophysics
Abstract Preliminary in vivo proton spectroscopic studies of the posterior chamber of the rat eye have been undertaken at 7 T. The Spatial and Chemical shift encoded Excitation (SPACE) localization sequence was used to acquire signals from 10-μl voxels and demonstrate the presence of metabolites associated with the vitreous humor, lens, retina, and the optic nerve. Localized T2 and T1 measurements of water in the vitreous humor indicate a relatively fluid environment. Susceptibility maps are used to demonstrate the difficulties of in vivo spectroscopic investigations in the anterior regions of the eye. Comments are made concerning the implications for spectral resolution in these regions.
Keyword 1H NMR spectroscopy
in vivo localized spectroscopy
ocular spectroscopy
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import
 
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