The developmental multiplicity and isoenzyme status of rat esterases

Holmes R.S. and Masters C.J. (1967) The developmental multiplicity and isoenzyme status of rat esterases. BBA - Enzymology, 146 1: 138-150.

Author Holmes R.S.
Masters C.J.
Title The developmental multiplicity and isoenzyme status of rat esterases
Journal name BBA - Enzymology
ISSN 0005-2744
Publication date 1967-09-12
Sub-type Article (original research)
Volume 146
Issue 1
Start page 138
End page 150
Total pages 13
Subject 2700 Medicine
Abstract 1. 1.|With the aim of clarifying the isoenzyme status of esterases, the developmental and physicochemical properties of these enzymes have been studied in an extensive range of rat tissues. 2. 2.|A total of 33 multiple forms of soluble esterase activity have been resolved, and the occurrence of these individual forms in the different tissues interrelated. 3. 3.|By means of substrate and inhibitor studies, these heteromorphs have been characterized into 4 main classes: carboxylesterases, arylesterases, acetylesterases and cholinesterases. 4. 4.|All of these classes are heterogenous-the soluble carboxylesterases existing as 15 separate forms, arylesterases 5, cholinesterases 10, and acetylesterases 3. 5. 5.|Further differentiation of the multiple forms in these classes has been achieved on the basis of the physicochemical and developmental parameters utilized. This treatment would appear to implicate at least 13 structural genes in the biosynthesis of soluble rat esterases.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import
Version Filter Type
Citation counts: Scopus Citation Count Cited 0 times in Scopus Article
Google Scholar Search Google Scholar
Created: Tue, 28 Jun 2016, 05:49:38 EST by System User