The presence and significance of intraepithelial mesenchymal cells in human foetal colon

Bell L. and Williams L. (1988) The presence and significance of intraepithelial mesenchymal cells in human foetal colon. Anatomy and Embryology, 177 4: 377-380. doi:10.1007/BF00315847


Author Bell L.
Williams L.
Title The presence and significance of intraepithelial mesenchymal cells in human foetal colon
Journal name Anatomy and Embryology   Check publisher's open access policy
ISSN 0340-2061
Publication date 1988
Sub-type Article (original research)
DOI 10.1007/BF00315847
Volume 177
Issue 4
Start page 377
End page 380
Total pages 4
Publisher Springer-Verlag
Subject 2710 Embryology
2702 Anatomy
1309 Developmental Biology
1307 Cell Biology
Abstract During an investigation of the morphogenesis of the human foetal colon, breaks in the basal lamina underlying the surface epithelium were frequently observed at 10 1/2-11 weeks. These occurred at those sites where the mesenchyme was sweeping up into the epithelium prior to the transformation of the epithelium from stratified to a single layer. At the same time numbers of mesenchymal cells appeared among the epithelial cells and some were observed actually in the process of passing through the gaps in the basal lamina. Close contact was apparent between some mesenchymal cells and basal epithelial cells through extended breaks in the basal lamina. Many of the mesenchymal cells within the epithelium contained numbers of apoptotic bodies. This suggests that one of the functions of the intra-epithelial mesenchymal cells is to remove the debris resulting from cell death which occurs in association with the re-arrangement of cells during development of the colon.
Keyword Apoptosis
Human foetal intestine
Intraepithelial cells
Mesenchyme
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import
 
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Created: Tue, 28 Jun 2016, 05:07:12 EST by System User