The effect of excess vitamin A on longbone growth in kittens

Clark L. (1970) The effect of excess vitamin A on longbone growth in kittens. Journal of Comparative Pathology, 80 4: . doi:10.1016/0021-9975(70)90062-9


Author Clark L.
Title The effect of excess vitamin A on longbone growth in kittens
Journal name Journal of Comparative Pathology   Check publisher's open access policy
ISSN 0021-9975
Publication date 1970
Sub-type Article (original research)
DOI 10.1016/0021-9975(70)90062-9
Volume 80
Issue 4
Total pages 1
Subject 1103 Clinical Sciences
Abstract Eight kittens were destroyed after receiving a high daily dose of vitamin A for 21 days or 30 days following weaning. Longbone pathology was studied in comparison with bones from pair-fed controls. Two kittens which had received similar treatment were returned to normal diets after the dosage period and destroyed some weeks later. In the kittens destroyed immediately after dosing the main changes were reduction in endochondral bone growth due to damage to epiphyseal plates, and osteoporosis due to cessation or retardation of osteoid production in the diaphyses. Retarded endochondral bone growth was accentuated in the two kittens allowed to recover after dosing, while bone formation in the diaphyses had returned to normal.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import
 
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Created: Tue, 28 Jun 2016, 03:47:32 EST by System User