On the location of cellular functions in perfused organs

Bass L. (1980) On the location of cellular functions in perfused organs. Journal of Theoretical Biology, 82 3: 347-351. doi:10.1016/0022-5193(80)90241-6


Author Bass L.
Title On the location of cellular functions in perfused organs
Journal name Journal of Theoretical Biology   Check publisher's open access policy
ISSN 1095-8541
Publication date 1980-02-07
Sub-type Article (original research)
DOI 10.1016/0022-5193(80)90241-6
Volume 82
Issue 3
Start page 347
End page 351
Total pages 5
Subject 1100 Agricultural and Biological Sciences
Abstract Rappaport's picture of liver cells performing specialized functions in spatially distinct zones arranged in relation to hepatic blood flow, is arrived at from a new direction. Previously published data from perfused rat livers eliminating labelled acetaminophen, both pre-formed and formed in the liver from phenacetin, are interpreted to imply that the formation takes place wholly upstream of the elimination. This analysis exemplifies a general method of mapping such functional zones in perfused organs.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import
 
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Created: Tue, 28 Jun 2016, 01:49:40 EST by System User