Bladder disease: A report based on the smooth muscle function in health and disease satellite meeting to the International Congress of Physiology

Doggrell S.A. (2001). Bladder disease: A report based on the smooth muscle function in health and disease satellite meeting to the International Congress of Physiology. In: , , (811-814). .

Author Doggrell S.A.
Title of paper Bladder disease: A report based on the smooth muscle function in health and disease satellite meeting to the International Congress of Physiology
Journal name Drugs of Today   Check publisher's open access policy
Publication Year 2001
Sub-type Fully published paper
ISSN 1699-3993
Volume 37
Issue 12
Start page 811
End page 814
Total pages 4
Abstract/Summary One of the satellite meetings to the International Congress of Physiological Sciences concerned smooth muscle function in health and disease. In this report I have highlighted one of the areas of disease that were discussed: namely, bladder disease. In the treatment of unstable bladder, antimuscarinic agents are effective but cause unacceptable side effects. Thus, in order to prevent the side effects, new antimuscarinic agents are being prepared that show selectivity for the bladder and new methods for local delivery of antimuscarinics to the bladder are being developed. Potential new targets for the unstable bladder include P2X receptors and the nerve growth factor pathway. In detrusor-external sphincter dyssynergia, there is evidence to support a clinical trial of nitric oxide donors. The unpleasant and painful condition of interstitial cystitis has, to date, proven difficult to treat. Preliminary clinical data suggests that the leukotriene D4 receptor antagonist montelukast may be useful in the treatment of IC.
Subjects 1313 Molecular Medicine
2736 Pharmacology (medical)
3004 Pharmacology
Q-Index Code E1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Conference Paper
Collection: Scopus Import
 
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Created: Tue, 28 Jun 2016, 01:16:38 EST by System User