Plant G-proteins come of age: breaking the bond with animal models

Trusov, Yuri and Botella, Jose R. (2016) Plant G-proteins come of age: breaking the bond with animal models. Frontiers in Chemistry, 4 24: 1-9. doi:10.3389/fchem.2016.00024

Author Trusov, Yuri
Botella, Jose R.
Title Plant G-proteins come of age: breaking the bond with animal models
Journal name Frontiers in Chemistry   Check publisher's open access policy
ISSN 2296-2646
Publication date 2016-05-24
Year available 2016
Sub-type Article (original research)
DOI 10.3389/fchem.2016.00024
Open Access Status DOI
Volume 4
Issue 24
Start page 1
End page 9
Total pages 9
Place of publication Lausanne, Switzerland
Publisher Frontiers Research Foundation
Collection year 2017
Language eng
Abstract G-proteins are universal signal transducers mediating many cellular responses. Plant G-protein signaling has been modeled on the well-established animal paradigm but accumulated experimental evidence indicates that G-protein-dependent signaling in plants has taken a very different evolutionary path. Here we review the differences between plant and animal G-proteins reported over past two decades. Most importantly, while in animal systems the G-protein signaling cycle is activated by seven transmembrane-spanning G-protein coupled receptors, the existence of these type of receptors in plants is highly controversial. Instead plant G-proteins have been proven to be functionally associated with atypical receptors such as the Arabidopsis RGS1 and a number of receptor-like kinases. We propose that, instead of the GTP/GDP cycle used in animals, plant G-proteins are activated/de-activated by phosphorylation/de-phosphorylation. We discuss the need of a fresh new look at these signaling molecules and provide a hypothetical model that departs from the accepted animal paradigm.
Keyword Heterotrimeric G-proteins
Plant signaling
Receptor-like kinases
Plant defense
Control of plant development
Extra-large G-proteins
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
School of Agriculture and Food Sciences
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