Interaction of Fluoride and Molybdenum on Dental Morphology in the Rat

Kruger B.J. (1966) Interaction of Fluoride and Molybdenum on Dental Morphology in the Rat. Journal of Dental Research, 45 3: 714-725. doi:10.1177/00220345660450033801


Author Kruger B.J.
Title Interaction of Fluoride and Molybdenum on Dental Morphology in the Rat
Journal name Journal of Dental Research   Check publisher's open access policy
ISSN 1544-0591
Publication date 1966
Sub-type Article (original research)
DOI 10.1177/00220345660450033801
Volume 45
Issue 3
Start page 714
End page 725
Total pages 12
Subject 3500 Dentistry
Abstract Eleven replications of a 2 by 2 factorial design were completed to study the main effects and the interaction of fluoride and molybdenum on dental morphology in the rat. This design permitted the measurement of within-litter effects by the treatments, which were administered twice daily from postnatal days 4 through 19, inclusively. The rats were destroyed at 21 days. The left maxillary first molars were sectioned along the maximum' mesiodistal diameter, and various morphologic features were measured by means of a calibrated eyepiece graticule at magnifications of X25, X44, and X125. None of the treatments altered the size of the tooth, as determined by the maximum mesiodistal diameter, but fluoride and the interaction of fluoride and molybdenum altered the widths of the fissures and the thickness of the enamel and the dentin lining the fissures. For the particular levels of fluoride and molybdenum used in this study, the interaction did not enhance the effect of fluoride alone, but instead depressed and reversed it. The possible significance of the findings have been discussed, and several suggestions for future investigation have been made.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import
 
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