Induced cell proliferation and the initiation of skin tumour formation in mice by ultraviolet light

Pound A.W. (1970) Induced cell proliferation and the initiation of skin tumour formation in mice by ultraviolet light. Pathology, 2 4: 269-275.

Author Pound A.W.
Title Induced cell proliferation and the initiation of skin tumour formation in mice by ultraviolet light
Journal name Pathology   Check publisher's open access policy
ISSN 1465-3931
Publication date 1970
Sub-type Article (original research)
Volume 2
Issue 4
Start page 269
End page 275
Total pages 7
Subject 2734 Pathology and Forensic Medicine
Abstract A single short exposure of the skin of mice to ultraviolet light did not produce any tumours, but a significant number of tumours developed when the exposure was followed by repeated applications of croton oil. Ultraviolet radiation therefore behaves as an initiating agent, resembling this action of some other carcinogens for the skin of mice. Treatment of the skin of the mice with acetic acid, xylene or croton oil 20 hours before irradiation increased the number of tumours. It is considered that cells induced to proliferate are more susceptible to the carcinogenic effect of ultraviolet radiation than their normal counterparts.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import
 
Versions
Version Filter Type
Citation counts: Scopus Citation Count Cited 0 times in Scopus Article
Google Scholar Search Google Scholar
Created: Tue, 14 Jun 2016, 03:30:17 EST by System User