Detection of cobalt deficiency in lactating heifers and their calves

Norton B.W. and Quirk M.F. (1988) Detection of cobalt deficiency in lactating heifers and their calves. The Journal of Agricultural Science, 110 3: 465-470. doi:10.1017/S0021859600082010


Author Norton B.W.
Quirk M.F.
Title Detection of cobalt deficiency in lactating heifers and their calves
Journal name The Journal of Agricultural Science   Check publisher's open access policy
ISSN 1469-5146
Publication date 1988
Sub-type Article (original research)
DOI 10.1017/S0021859600082010
Volume 110
Issue 3
Start page 465
End page 470
Total pages 6
Subject 1102 Cardiovascular Medicine and Haematology
1103 Clinical Sciences
1311 Genetics
Abstract Responses in live weight, milk production and calf growth to cobalt supplementation of groups of three and four pregnant heifers were measured to assess the value of serum vitamin B 12concentrations and the urinary concentrations of methylmalonic acid (MMA) and formiminoglutamic acid (FIGLU) for the detection of cobalt deficiency in cattle. The administration of cobalt bullets to pregnant heifers, grazing pastures containing between 0.03 and 0.05 mg/kg cobalt, had no effect on either their live-weight change or milk production, or on the birth weight of their calves. MMA and FIGLU concentrations in the urine of unsupplemented heifers were low for the majority of the experimental period, although the concentrations of vitamin B 12in their serum (< 100 pg/ml) were in the range usually considered indicative of cobalt deficiency. Calves from unsupplemented heifers had lower growth rates during the first 3 months of life and this was associated with intakes of 0.24-0.46 µg/day of vitamin B 12from milk, only 1–3 % of those received by calves from supplemented heifers. Poor growth was associated with high urinary FIGLU concentrations, which increased from 500 to 2000 µmol/1 between 1 and 3 months of age but decreased to less than 100 µmol/1 between 3 and 4.5 months of age. Urinary FIGLU was a more reliable indicator of vitamin B 12deficiency in suckled calves than was urinary MMA, elevated levels of which were observed only at 3 months of age. The concentration of vitamin B 12in the serum of calves from unsupplemented heifers was consistently less than 100 pg/ml, but was not a reliable indicator of their functional vitamin B 12status, as judged by urinary concentrations of FIGLU and/or MMA.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import
 
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