Ovarian tumor antigens: Preliminary histological investigation

Daunter B., Jaa-Kwee D., Miklosi S. and Wright G. (1986) Ovarian tumor antigens: Preliminary histological investigation. Gynecologic Oncology, 23 3: 364-370. doi:10.1016/0090-8258(86)90139-3


Author Daunter B.
Jaa-Kwee D.
Miklosi S.
Wright G.
Title Ovarian tumor antigens: Preliminary histological investigation
Journal name Gynecologic Oncology   Check publisher's open access policy
ISSN 1095-6859
Publication date 1986
Sub-type Article (original research)
DOI 10.1016/0090-8258(86)90139-3
Volume 23
Issue 3
Start page 364
End page 370
Total pages 7
Subject 2729 Obstetrics and Gynaecology
2730 Oncology
Abstract The immunoglobulin IgG was isolated from the immune complexes obtained from the ascitic fluids of patients with ovarian serous cystadenocarcinoma. The IgG isolates did not react in immunoperoxidase staining of normal ovarian, fallopian tube, or endocervical tissue. In contrast, the IgG isolates did react in immunoperoxidase staining of autologous and allogeneic ovarian cancer tissue. However, the staining was variable in terms of areas of positivity and was completely absent in some serial sections. This variability was also evident in control sections of an ovarian mucinous cystadenocarcinoma that was positive for the carcinoembryonic antigen. In addition, it appears that serous and mucinous ovarian cancers may share common antigenic determinants. These results demonstrate the antigenic heterogenous nature of ovarian cancer.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import
 
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Created: Tue, 14 Jun 2016, 00:44:32 EST by System User