Algae genome-scale reconstruction, modelling and applications

Dal'Molin, Cristiana G. O. and Nielsen, Lars K. (2016). Algae genome-scale reconstruction, modelling and applications. In Michael A. Borowitzka, John Beardall and John A. Raven (Ed.), The Physiology of Microalgae (pp. 591-598) Switzerland: Springer International Publishing. doi:10.1007/978-3-319-24945-2_22

Author Dal'Molin, Cristiana G. O.
Nielsen, Lars K.
Title of chapter Algae genome-scale reconstruction, modelling and applications
Title of book The Physiology of Microalgae
Place of Publication Switzerland
Publisher Springer International Publishing
Publication Year 2016
Sub-type Research book chapter (original research)
DOI 10.1007/978-3-319-24945-2_22
Open Access Status Not Open Access
Year available 2016
Series Developments in Applied Phycology
ISBN 9783319249438
Editor Michael A. Borowitzka
John Beardall
John A. Raven
Volume number 6
Chapter number 22
Start page 591
End page 598
Total pages 8
Total chapters 24
Collection year 2017
Language eng
Formatted Abstract/Summary
Driven by revolutionary advances in high-throughput omics technologies, genome-scale metabolic reconstructions are a common denominator in systems biology and are available for a wide range of organisms. The constraint modelling formulation approach derived from the metabolic reconstructions have been successfully used to a number of applications including: metabolic engineering, biofuel research, genome functional annotation, omics data integration and in particular global pathway analysis. Recent advances have been made on plant and algae genome-scale metabolic reconstruction. In this book chapter we present the genome-scale reconstructions based on Chlamydomonas reinhardtii along with modelling formulation. We also give a few examples of the use of genome-scale models to algae biotechnological applications.
Keyword Flux balance analysis
Metabolic network
Systems biology
Chlamydomonas Reinhardtii
Escherichia Coli
Glycolate metabolism
Q-Index Code B1
Q-Index Status Provisional Code
Institutional Status UQ

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