No relationship between binocular rivalry rate and eye-movement profiles in healthy individuals: a Bayes factor analysis

Law, Phillip C. F., Paton, Bryan K., Riddiford, Jacqueline A., Gurvich, Caroline T., Ngo, Trung T. and Miller, Steven M. (2015) No relationship between binocular rivalry rate and eye-movement profiles in healthy individuals: a Bayes factor analysis. Perception, 44 6: 643-661. doi:10.1177/0301006615594267


Author Law, Phillip C. F.
Paton, Bryan K.
Riddiford, Jacqueline A.
Gurvich, Caroline T.
Ngo, Trung T.
Miller, Steven M.
Title No relationship between binocular rivalry rate and eye-movement profiles in healthy individuals: a Bayes factor analysis
Journal name Perception   Check publisher's open access policy
ISSN 0301-0066
1468-4233
Publication date 2015-06-01
Sub-type Article (original research)
DOI 10.1177/0301006615594267
Volume 44
Issue 6
Start page 643
End page 661
Total pages 19
Place of publication London, United Kingdom
Publisher Sage Publications
Collection year 2016
Language eng
Formatted abstract
Binocular rivalry (BR) is an intriguing phenomenon in which conflicting images are presented, one to each eye, resulting in perceptual alternations between each image. The rate of BR has been proposed as a potential endophenotype for bipolar disorder because (a) it is well established that this highly heritable psychiatric condition is associated with slower BR rate than in controls, and (b) an individual’s BR rate is approximately 50% genetically determined. However, eye movements (EMs) could potentially account for the slow BR trait given EM anomalies are observed in psychiatric populations, and there has been report of an association between saccadic rate and BR rate in healthy individuals. Here, we sought to assess the relationship between BR rate and EMs in healthy individuals (N = 40, mean age = 34.4) using separate BR and EM tasks, with the latter measuring saccades during anticipatory, antisaccade, prosaccade, self-paced, free-viewing, and smooth-pursuit tasks. No correlation was found between BR rate and any EM measure for any BR task (p > .01) with substantial evidence favoring this lack of association (BF01 > 3). This finding is in contrast to previous data and has important implications for using BR rate as an endophenotype. If replicated in clinical psychiatric populations, EM interpretations of the slow BR trait can be excluded.
Keyword Binocular rivalry
Bipolar disorder
Endophenotype
Individual variation
Perceptual alternation rate
Saccadic eye movements
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
University of Queensland Library Staff Publications and Presentations
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 1 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 1 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Wed, 08 Jun 2016, 03:01:35 EST by System User on behalf of Learning and Research Services (UQ Library)