Evaluation of monitoring schemes for wastewater-based epidemiology to identify drug use trends using cocaine, methamphetamine, MDMA and methadone

Humphries, Melissa A., Bruno, Raimondo, Lai, Foon Yin, Thai, Phong K., Holland, Barbara R., O'Brien, Jake W., Ort, Christoph and Mueller, Jochen F. (2016) Evaluation of monitoring schemes for wastewater-based epidemiology to identify drug use trends using cocaine, methamphetamine, MDMA and methadone. Environmental Science and Technology, 50 9: 4760-4768. doi:10.1021/acs.est.5b06126


Author Humphries, Melissa A.
Bruno, Raimondo
Lai, Foon Yin
Thai, Phong K.
Holland, Barbara R.
O'Brien, Jake W.
Ort, Christoph
Mueller, Jochen F.
Title Evaluation of monitoring schemes for wastewater-based epidemiology to identify drug use trends using cocaine, methamphetamine, MDMA and methadone
Journal name Environmental Science and Technology   Check publisher's open access policy
ISSN 1520-5851
0013-936X
Publication date 2016-05-03
Year available 2016
Sub-type Article (original research)
DOI 10.1021/acs.est.5b06126
Open Access Status Not Open Access
Volume 50
Issue 9
Start page 4760
End page 4768
Total pages 9
Place of publication Washington, DC United States
Publisher American Chemical Society
Collection year 2017
Language eng
Abstract Wastewater-based epidemiology is increasingly being used as a tool to monitor drug use trends. To minimize costs, studies have typically monitored a small number of days. However, cycles of drug use may display weekly and seasonal trends that affect the accuracy of monthly or annual drug use estimates based on a limited number of samples. This study aimed to rationalize sampling methods for minimizing the number of samples required while maximizing information about temporal trends. A range of sampling strategies were examined: (i) targeted days (e.g., weekends), (ii) completely random or stratified random sampling, and (iii) a number of sampling strategies informed by known weekly cycles in drug use data. Using a time-series approach, analysis was performed for four drugs (MDMA, methamphetamine, cocaine, methadone) collected through a continuous sampling program over 14 months. Results showed, for drugs with weekly cycles (MDMA, methamphetamine and cocaine in this sample), sampling strategies which made use of those weekly cycles required fewer samples to obtain similar information as sampling 5 days per week and had better accuracy than stratified random sampling techniques.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
National Research Centre for Environmental Toxicology Publications
Advanced Water Management Centre Publications
 
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