Cannabis use and mental health in young people: cohort study

Patton, George C., Coffey, Carolyn, Carlin, John B., Degenhardt, Louisa, Lynskey, Michael and Hall, Wayne (2002) Cannabis use and mental health in young people: cohort study. BMJ, 325 7374: 1195-1198. doi:10.1136/bmj.325.7374.1195

Author Patton, George C.
Coffey, Carolyn
Carlin, John B.
Degenhardt, Louisa
Lynskey, Michael
Hall, Wayne
Title Cannabis use and mental health in young people: cohort study
Journal name BMJ   Check publisher's open access policy
ISSN 0959-8146
Publication date 2002-11-23
Sub-type Article (original research)
DOI 10.1136/bmj.325.7374.1195
Open Access Status DOI
Volume 325
Issue 7374
Start page 1195
End page 1198
Total pages 4
Place of publication London
Publisher British Medical Association
Language eng
Formatted abstract
To determine whether cannabis use in adolescence predisposes to higher rates of depression and anxiety in young adulthood.


Seven wave cohort study over six years.

44 schools in the Australian state of Victoria.


A statewide secondary school sample of 1601 students aged 14-15 followed for seven years.

Main outcome measure:

Interview measure of depression and anxiety (revised clinical interview schedule) at wave 7.


Some 60% of participants had used cannabis by the age of 20; 7% were daily users at that point. Daily use in young women was associated with an over fivefold increase in the odds of reporting a state of depression and anxiety after adjustment for intercurrent use of other substances (odds ratio 5.6, 95% confidence interval 2.6 to 12). Weekly or more frequent cannabis use in teenagers predicted an approximately twofold increase in risk for later depression and anxiety (1.9, 1.1 to 3.3) after adjustment for potential baseline confounders. In contrast, depression and anxiety in teenagers predicted neither later weekly nor daily cannabis use.


Frequent cannabis use in teenage girls predicts later depression and anxiety, with daily users carrying the highest risk. Given recent increasing levels of cannabis use, measures to reduce frequent and heavy recreational use seem warranted.
Keyword Medicine, General & Internal
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Public Health Publications
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 376 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 0 times in Scopus Article
Google Scholar Search Google Scholar
Created: Mon, 13 Aug 2007, 13:17:09 EST