Early prediction of poor outcome in extremely low birth weight infants by classification tree analysis

Ambalavanan, N., Baibergenova, A., Carlo, W. A., Saigal, S., Schmidt, B. and Thorpe, K. E. (2006) Early prediction of poor outcome in extremely low birth weight infants by classification tree analysis. Journal of Pediatrics, 148 4: 438-444. doi:10.1016/j.jpeds.2005.11.042


Author Ambalavanan, N.
Baibergenova, A.
Carlo, W. A.
Saigal, S.
Schmidt, B.
Thorpe, K. E.
Title Early prediction of poor outcome in extremely low birth weight infants by classification tree analysis
Journal name Journal of Pediatrics   Check publisher's open access policy
ISSN 0022-3476
Publication date 2006
Sub-type Article (original research)
DOI 10.1016/j.jpeds.2005.11.042
Volume 148
Issue 4
Start page 438
End page 444
Total pages 1
Language eng
Subject 2735 Pediatrics, Perinatology, and Child Health
Abstract Objective: To predict death or neurodevelopmental impairment (NDI) in extremely low birth weight infants by classification trees with recursive partitioning and automatic selection of optimal cut points of variables. Study design: Data from the Trial of Indomethacin Prophylaxis in Preterms were randomly divided into development (n = 784) and validation sets (n = 262). Three models were developed for the combined outcome of death (8 days to 18 months) or NDI (cerebral palsy, cognitive delay, deafness, or blindness at 18 months corrected age): antenatal: antenatal data; early neonatal: antenatal + first 3 days data; and first week: antenatal, first 3 days, and 4th to 8th days data. Decision trees were tested on the validation set. Results: Variables associated with death/NDI in each model were: Antenatal: Gestation ≤25.5 weeks and antenatal steroids <7 days. Early neonatal: Birth weight ≤787 g and fluid intake >101 mL/kg/d. First week: Birth weight ≤787 g: transfusion >3 mL/kg/d. Birth weight >787 g: cranial echodense intraparenchymal lesion and transfusion >11 mL/kg/d. Correct classification rates were 61% to 62% for all models. Conclusions: The ability to predict long-term morbidity/death in extremely low birth weight infants does not improve significantly over the first week of life. Effects of different variables depend on age.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collections: ResearcherID Downloads
Scopus Import
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 30 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 32 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Mon, 23 May 2016, 16:01:14 EST by System User